胰岛素对大鼠5-甲氧基色胺诱导的湿狗摇行为的影响。
The influence of insulin on 5-methoxytryptamine-induced wet dog shake behavior in rats.
作者信息
Kleinrok Z, Juszkiewicz M
出版信息
Pol J Pharmacol Pharm. 1986 Sep-Dec;38(5-6):443-8.
PMID:3554184
Abstract
The administration of insulin intraperitoneally (2 U/kg) and intracerebroventricularly (4 U per rat) caused an increased wet dog shake response to 5-methoxytryptamine, suggesting an increase in reactivity of central serotonergic structures. Glucose, in doses which prevented hypoglycemia virtually did not change the effect of insulin.
摘要
腹腔注射胰岛素（2单位/千克）和脑室内注射胰岛素（每只大鼠4单位）会使对5-甲氧基色胺的湿狗抖反应增强，这表明中枢5-羟色胺能结构的反应性增加。能预防低血糖的剂量的葡萄糖实际上并未改变胰岛素的作用。
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