Zhou Qinghua, Wang Bin, Li Jia, Jin Zanhui, Li Haiyang, Chen Jinyuan
Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology Hangzhou 310014 People's Republic of China
Key Laboratory of Tea Biology and Resources Utilization, Ministry of Agriculture, Tea Research Institute, Chinese Academy of Agricultural Sciences Hangzhou 310008 People's Republic of China.
RSC Adv. 2018 May 16;8(32):18067-18073. doi: 10.1039/c8ra02611d. eCollection 2018 May 14.
Ion mobility spectrometry (IMS) has become a potential technique for the rapid detection of organophosphorus pesticides (OPPs). However, using only the commonly-used reactant ion (Ac)H(HO) , some OPPs are difficult to distinguish due to their severely overlapping ion peaks. In this study, the switching of reactant ions ((Ac)H(HO) , O (HO) and Cl(HO) ) in a stand-alone photoionization ion mobility spectrometer was realized by on-line switching the polarity of high voltage and dopant species. Multiple reactant ions were employed to establish the characteristic patterns for the tested OPPs, including fenthion, dursban, dimethoate, malathion, fenitrothion, imidan and isocarbophos. The tested OPPs were represented on a heat map and a three-dimensional coordinate system based on the patterns, from which they could be readily identified. Under optimal conditions, the limits of detection (LODs) of the tested OPPs were evaluated to be 0.3-2.7 ng, and satisfactory repeatability was demonstrated by the obtained relative standard deviations (RSDs) of 4.8% to 14.7%. Finally, Chinese cabbage extract spiked with dursban and malathion was detected by the proposed ion mobility spectrometer, demonstrating its applicability for the simultaneous identification of coexisting OPPs in real samples.
离子迁移谱（IMS）已成为快速检测有机磷农药（OPPs）的一种潜在技术。然而，仅使用常用的反应离子（Ac）H(HO) 时，一些有机磷农药由于其离子峰严重重叠而难以区分。在本研究中，通过在线切换高压极性和掺杂剂种类，在独立的光电离离子迁移谱仪中实现了反应离子（(Ac)H(HO) 、O (HO) 和Cl(HO) ）的切换。采用多种反应离子建立了所测试有机磷农药（包括倍硫磷、毒死蜱、乐果、马拉硫磷、杀螟硫磷、亚胺硫磷和水胺硫磷）的特征 模式。基于这些模式，将所测试的有机磷农药呈现在热图和三维坐标系上，从中可以很容易地识别它们。在最佳条件下，所测试有机磷农药的检测限（LODs）评估为0.3 - 2.7 ng，所获得的4.8%至14.7%的相对标准偏差（RSDs）表明具有令人满意的重复性。最后，用所提出的离子迁移谱仪检测了添加了毒死蜱和马拉硫磷的大白菜提取物，证明了其对实际样品中共存有机磷农药同时鉴定的适用性。
