Recent advances on GPIb-IX-V complex.
作者信息
Li Renhao
机构信息
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
出版信息
Platelets. 2022 Aug 18;33(6):809-810. doi: 10.1080/09537104.2022.2075146. Epub 2022 May 11.
Abstract
摘要
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Recent advances on GPIb-IX-V complex.糖蛋白Ib-IX-V复合物的最新进展。
Platelets. 2022 Aug 18;33(6):809-810. doi: 10.1080/09537104.2022.2075146. Epub 2022 May 11.
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Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit.中性粒细胞蛋白酶组织蛋白酶G对人血小板糖蛋白Ib-IX受体具有蛋白水解活性：糖蛋白Ibα亚基内切割位点的特征分析
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GPIb-IX-V and platelet clearance.GPIb-IX-V 和血小板清除。
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[Abnormal expression of the platelet membrane receptor glycoprotein Ib-IX-V complex in transiently transfected HEK 293T cells].[血小板膜受体糖蛋白Ib-IX-V复合物在瞬时转染的人胚肾293T细胞中的异常表达]
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本文引用的文献
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Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells.SARS-CoV-2 通过激活血小板表明受感染细胞释放了具有活性的组织因子。
Blood Adv. 2022 Jun 28;6(12):3593-3605. doi: 10.1182/bloodadvances.2022007444.
2
Fast clearance of platelets in a commonly used mouse model for GPIbα is impeded by an anti-GPIbβ antibody derivative.在常用于 GPIbα 的小鼠模型中，血小板清除速度很快，一种抗 GPIbβ 抗体衍生物会阻碍其清除。
J Thromb Haemost. 2022 Jun;20(6):1451-1463. doi: 10.1111/jth.15702. Epub 2022 Mar 29.
3
Platelets mediate inflammatory monocyte activation by SARS-CoV-2 spike protein.血小板通过 SARS-CoV-2 刺突蛋白介导炎症性单核细胞的激活。
J Clin Invest. 2022 Feb 15;132(4). doi: 10.1172/JCI150101.
4
Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets.机械分子信号在血小板中导致 FC 非依赖性免疫性血小板减少症。
Blood. 2018 Feb 15;131(7):787-796. doi: 10.1182/blood-2017-05-784975. Epub 2017 Dec 4.
5
Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation.血小板聚集所必需的糖蛋白Ibα-凝血酶复合物的晶体结构。
Science. 2003 Jul 11;301(5630):222-6. doi: 10.1126/science.1083917.
6
Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha.通过与血小板糖蛋白Ibalpha的不同相互作用对α-凝血酶功能的调节
Science. 2003 Jul 11;301(5630):218-21. doi: 10.1126/science.1084183.
7
Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.糖蛋白Ibalpha及其与血管性血友病因子A1结构域复合物的结构。
Science. 2002 Aug 16;297(5584):1176-9. doi: 10.1126/science.107355.
8
Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome.血小板功能障碍小鼠模型的建立与挽救：伯纳德-索利尔综合征
Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2803-8. doi: 10.1073/pnas.050582097.
9
10
Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis.通过一维和二维十二烷基硫酸钠-聚丙烯酰胺凝胶电泳分析伯纳德-索利尔血小板的糖蛋白和蛋白质组成。
J Clin Invest. 1981 May;67(5):1431-40. doi: 10.1172/jci110172.
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