Yıldız Munise, Kozanhan Betül, Aydoğan Eyüp, Tire Yasin, Sekmenli Tamer
Department of Anaesthesiology and Reanimation, Health and Science University, Konya City Hospital, Konya, Turkey.
Department of Anaesthesiology and Reanimation, Bursa Gürsu State Hospital, Bursa, Turkey.
Turk J Anaesthesiol Reanim. 2022 Apr;50(2):121-128. doi: 10.5152/TJAR.2022.21602.
Millions of children are exposed to anaesthetic drugs every day; however, the possible adverse effects of these agents on the central nervous system remain controversial. This study evaluated anaesthesiologists' and pediatric surgeons' knowledge and daily practices regarding anaesthesia-induced neurotoxicity.
A survey consisting of 12 questions was sent to members of the Turkish Anaesthesiology and Reanimation Association and the Turkish Pediatric Surgery Association via the Google forms program.
A total of 202 anaesthesiologists and 51 pediatric surgeons participated in this survey. The results demonstrate that anaesthesiologists and surgeons are aware of the risk of anaesthesia-related neurotoxicity and are willing to take action. Approximately, half of the anaesthesiologists and pediatric surgeons expected to postpone operations lasting at least 3 hours for patients <3 years of age. Also, one-third of the anaesthesiologists would seek feasible and more reliable alternative anaesthetic strategies.
More than two-thirds of the participants knew about the US Food and Drug Administration neurotoxicity warning; however, uncertainty about anaesthesia-related neurotoxicity is ongoing. Many questions remain unanswered. The results of large-scale prospective randomized studies to evaluate the effect of anaesthetics and surgery on the cognitive development of pediatric patients are needed.
每天有数百万儿童接触麻醉药物；然而，这些药物对中枢神经系统可能产生的不良影响仍存在争议。本研究评估了麻醉医生和小儿外科医生关于麻醉诱导神经毒性的知识及日常实践。
通过谷歌表单程序向土耳其麻醉与复苏协会和土耳其小儿外科学会的成员发送了一份包含12个问题的调查问卷。
共有202名麻醉医生和51名小儿外科医生参与了本次调查。结果表明，麻醉医生和外科医生意识到了与麻醉相关的神经毒性风险，并愿意采取行动。大约一半的麻醉医生和小儿外科医生期望为3岁以下的患者推迟至少持续3小时的手术。此外，三分之一的麻醉医生会寻求可行且更可靠的替代麻醉策略。
超过三分之二的参与者知晓美国食品药品监督管理局的神经毒性警告；然而，与麻醉相关的神经毒性仍存在不确定性。许多问题仍未得到解答。需要开展大规模前瞻性随机研究以评估麻醉和手术对小儿患者认知发育的影响。
