Ali Aly Bahadur, Khan Fauzia
Department of Anaesthesiology, Aga Khan University, Karachi, Pakistan.
Turk J Anaesthesiol Reanim. 2022 Apr;50(2):129-134. doi: 10.5152/TJAR.2021.1104.
The objective of this observational study was to determine the incidence of emergence delirium (ED) and its association with preoperative anxiety using the modified Yale preoperative anxiety scale and paediatric anaesthesia emergence delirium scale, in a tertiary care institution in South Asia.
A total of 250 children of 2-8 years of age (of either gender, American Society of Anaesthesiology classification I or II, undergoing infra umbilical surgery, using caudal block for analgesia) were enrolled and the study was completed. The primary outcome measure was the presence of ED using the paediatric anaesthesia emergence delirium score. A cut-off value equal to or more than 12 at any time point was taken as ED. The secondary measure was preoperative anxiety, measured using the modified Yale preoperative anxiety scale at 30 minutes before going into the operating room. A cut-off score of 30 was used.
The median age of the children was thirty-six months IQR (24-60). There were 230 (91%) males and 20 (9%) females. Twenty-two percent of the children experienced emergence delirium. One-point increase of modified Yale preoperative anxiety scale anxiety score was significantly associated with 1.23 times the odds of emergence delirium OR =1.23 (1.16-1.29) as compared with those without emergence delirium.
The incidence of emergence delirium in our cohort was 22.4%, and there was a significant association between preoperative anxiety and emergence delirium.
本观察性研究的目的是在南亚的一家三级医疗机构中,使用改良耶鲁术前焦虑量表和小儿麻醉苏醒期谵妄量表,确定苏醒期谵妄(ED)的发生率及其与术前焦虑的关联。
共纳入250名2至8岁的儿童(不限性别,美国麻醉医师协会分级为I或II级,接受脐下手术,采用骶管阻滞镇痛),并完成研究。主要结局指标是使用小儿麻醉苏醒期谵妄评分来判断是否存在ED。在任何时间点,评分等于或高于12分被视为ED。次要指标是术前焦虑,在进入手术室前30分钟使用改良耶鲁术前焦虑量表进行测量。采用的临界评分为30分。
儿童的中位年龄为36个月,四分位间距为(24 - 60)。有230名(91%)男性和20名(9%)女性。22%的儿童出现了苏醒期谵妄。与未出现苏醒期谵妄的儿童相比,改良耶鲁术前焦虑量表焦虑评分每增加1分,出现苏醒期谵妄的几率显著增加1.23倍,比值比=1.23(1.16 - 1.29)。
我们队列中苏醒期谵妄的发生率为22.4%,术前焦虑与苏醒期谵妄之间存在显著关联。