Departamento de Obstetrícia e Ginecologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil.
Departamento de Protese da Faculdade de Odontologia da Universidade de São Paulo, Sao Paulo, Brazil.
Menopause. 2022 Jun 1;29(6):728-733. doi: 10.1097/GME.0000000000001962.
To assess the correlation between menopausal symptoms and pain caused by temporomandibular disorder (TMD) and the impact of sociodemographic factors on the association.
In this cross-sectional study, a total of 74 women with TMD symptoms were enrolled and divided into three groups according to the Stages of Reproductive Aging Workshop + 10 (STRAW + 10) criteria: G1 (n = 25, late menopausal transition), G2 (n = 30, early postmenopause), and G3 (n = 19, late postmenopause). Sociodemographic data were collected, along with data on menopausal symptoms (Blatt-Kupperman menopausal index) and TMD-induced pain (craniomandibular index). Statistical analysis was performed using a chi-squared test and linear correlation tests (Spearman and Pearson).
Analysis of the three groups showed that TMD-induced pain was more intense in G1 than in G3 (P = 0.0426, r = 0.2364, r2 = 0.05589), and menopausal symptoms correlated with the intensity of TMD-induced pain (P = 0.0004, r = 0.4020). This correlation was more significant during the late menopausal transition (G1: P = 0.0267, r = 0.4427, r2 = 0.1960). In G2, women with fewer than 4 years of schooling had a higher total Blatt- Kupperman menopausal index score (17.0 ± 85.0) and craniomandibular index (0.29 ± 0.23) than women with more than 4 years of schooling (P = 0.02 for both indices).
Our results suggest that TMD-induced pain and menopausal symptoms are correlated, and more strongly so in the late menopausal transition. Additionally, sociodemographic factors, such as schooling, have a major influence on symptoms in early postmenopause. Performing the TMD evaluation during the climacteric period may be important.
评估绝经症状与颞下颌关节紊乱（TMD）疼痛之间的相关性，以及社会人口因素对两者关联的影响。
本横断面研究共纳入 74 例 TMD 症状女性患者，根据生殖衰老研讨会+10（STRAW + 10）标准分为三组：G1（n=25，绝经过渡期晚期）、G2（n=30，绝经早期）和 G3（n=19，绝经后期）。收集社会人口学数据、绝经症状（Blatt-Kupperman 绝经指数）和 TMD 相关疼痛（颅颌指数）数据。采用卡方检验和线性相关检验（Spearman 和 Pearson）进行统计分析。
三组分析显示，G1 的 TMD 相关疼痛强度大于 G3（P=0.0426，r=0.2364，r2=0.05589），且绝经症状与 TMD 相关疼痛强度相关（P=0.0004，r=0.4020）。这种相关性在绝经过渡期晚期更为显著（G1：P=0.0267，r=0.4427，r2=0.1960）。在 G2 中，受教育程度少于 4 年的女性总 Blatt-Kupperman 绝经指数评分（17.0±85.0）和颅颌指数（0.29±0.23）均高于受教育程度大于 4 年的女性（两个指数 P 值均为 0.02）。
我们的结果表明，TMD 相关疼痛与绝经症状相关，在绝经过渡期晚期相关性更强。此外，社会人口因素，如教育程度，对绝经早期的症状有重大影响。在绝经期进行 TMD 评估可能很重要。
