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Brazilian immunology in Caxambu: beyond vaccination, a tribute to the pioneers of basic research in Chagas disease.

作者信息

Scharfstein Julio

机构信息

Universidade Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho, Laboratório de Imunologia Molecular e Celular.

出版信息

Mem Inst Oswaldo Cruz. 2022 May 9;117:e210314chgsb. doi: 10.1590/0074-02760210314chgsb. eCollection 2022.

DOI:10.1590/0074-02760210314chgsb
PMID:35544861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9088418/
Abstract
摘要

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1
Brazilian immunology in Caxambu: beyond vaccination, a tribute to the pioneers of basic research in Chagas disease.卡桑布的巴西免疫学：超越疫苗接种，向恰加斯病基础研究的先驱致敬。
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XXV Annual meeting on Basic Research in Chagas Disease. XIV meeting of Brazilian Society of Protozoology. Caxambu, Brazil, 11-13 November 1998. Abstracts.查加斯病基础研究第25届年会。巴西原生动物学会第14届会议。1998年11月11日至13日，巴西卡尚布。摘要
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6
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XII Meeting of Brazilian Society of Protozoology and XXIII Annual meeting on Basic Research in Chagas' Disease. Caxambu, MG, Brasil, 5-8 November 1996. Abstracts.
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Proceedings of the XIX annual meeting on Basic Research in Chagas' disease and the VIII meeting of the Brazilian Society of Protozoology. Caxambu, November 10-13, 1993. Abstracts.
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Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.低剂量候选疟疾疫苗 R21 联合 Matrix-M 佐剂，季节性接种在布基纳法索儿童中的效果：一项随机对照试验。
Lancet. 2021 May 15;397(10287):1809-1818. doi: 10.1016/S0140-6736(21)00943-0. Epub 2021 May 5.
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Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility.模拟新型冠状病毒肺炎（COVID-19）在金黄地鼠模型中的临床和病理表现：对疾病发病机制和传染性的影响。
Clin Infect Dis. 2020 Dec 3;71(9):2428-2446. doi: 10.1093/cid/ciaa325.
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A prophylactic α-Gal-based glycovaccine effectively protects against murine acute Chagas disease.
一种基于α-半乳糖的预防性糖疫苗能有效预防小鼠急性恰加斯病。
NPJ Vaccines. 2019 Mar 22;4:13. doi: 10.1038/s41541-019-0107-7. eCollection 2019.
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The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family.与半胱氨酸蛋白酶复合的查加辛结构阐明了一个抑制剂家族的结合模式和进化过程。
Structure. 2007 May;15(5):535-43. doi: 10.1016/j.str.2007.03.012.
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The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites.环子孢子蛋白是经辐射的子孢子中的一种免疫显性保护性抗原。
Nature. 2006 Dec 14;444(7121):937-40. doi: 10.1038/nature05361. Epub 2006 Dec 6.
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Protective immunity against trypanosoma cruzi infection in a highly susceptible mouse strain after vaccination with genes encoding the amastigote surface protein-2 and trans-sialidase.用编码无鞭毛体表面蛋白-2和转唾液酸酶的基因接种后，在高度易感小鼠品系中对克氏锥虫感染的保护性免疫。
Hum Gene Ther. 2004 Sep;15(9):878-86. doi: 10.1089/hum.2004.15.878.
7
The surface coat of the mammal-dwelling infective trypomastigote stage of Trypanosoma cruzi is formed by highly diverse immunogenic mucins.克氏锥虫寄生于哺乳动物的感染性锥鞭毛体阶段的表面包被由高度多样的免疫原性黏蛋白构成。
J Biol Chem. 2004 Apr 16;279(16):15860-9. doi: 10.1074/jbc.M314051200. Epub 2004 Jan 28.
8
The Syrian hamster as a model for the dilated cardiomyopathy of Chagas' disease: a quantitative echocardiographical and histopathological analysis.叙利亚仓鼠作为恰加斯病扩张型心肌病的模型：定量超声心动图和组织病理学分析。
Microbes Infect. 2003 Oct;5(12):1116-24. doi: 10.1016/j.micinf.2003.07.001.
9
Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi.来自慢性恰加斯病患者的溶细胞性抗α-半乳糖基抗体可识别克氏锥虫黏蛋白样糖基磷脂酰肌醇锚定糖蛋白上的新型O-连接寡糖。
Biochem J. 1994 Dec 15;304 ( Pt 3)(Pt 3):793-802. doi: 10.1042/bj3040793.
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Biosynthesis of Pb44, the protective antigen of sporozoites of Plasmodium berghei.伯氏疟原虫子孢子保护性抗原Pb44的生物合成
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