Universidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Montería, Colombia.
Universidad del Rosario, Facultad de Ciencias Naturales, Centro de Investigaciones en Microbiología y Biotecnología-UR, Bogotá, Colombia.
Mem Inst Oswaldo Cruz. 2022 May 9;117:e210375. doi: 10.1590/0074-02760210375. eCollection 2022.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus of zoonotic origin that can bind to ACE2 receptors on the cells of many wild and domestic mammals. Studies have shown that the virus can circulate among animals mutate, lead to animal-to-human zoonotic jump, and further onward spread between humans. Infection in pets is unusual, and there are few human-to-pet transmission reports worldwide.
To describe the SARS-CoV-2 infection in a domestic animal in Córdoba, Colombian Caribbean region.
A cross-sectional molecular surveillance study was carried out, oral and rectal swabs were taken from cats and dogs living with people diagnosed with coronavirus disease 2019 (COVID-19).
SARS-CoV-2 was found in a cat living with a person with COVID-19. Genome sequencing showed that the B.1.111 lineage caused the infection in the cat. The owner's sample could not be sequenced. The lineage is predominant in Colombia, and this variant is characterised by the presence of the D614D and Q57H mutation.
The present work is the first report of an infected cat with SARS-CoV-2 with whole-genome sequencing in Colombia. It highlights the importance of detecting SARS-CoV-2 mutations that could promote the transmissibility of this new coronavirus. There is still a significant information gap on human-to-cat-to-human infection; we encourage self-isolation measures between COVID-19 patients and companion animals. The findings of this study give a preliminary view of the current panorama of SARS-CoV-2 infection in animals in Colombia.
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）是一种源自动物的病毒，可以与许多野生动物和家养哺乳动物细胞上的 ACE2 受体结合。研究表明，该病毒可以在动物中传播并发生变异，导致动物向人类的人畜共患病跳跃，进而在人与人之间进一步传播。宠物感染并不常见，全球范围内鲜有人类向宠物传播的报告。
描述哥伦比亚加勒比地区科尔多瓦的一种家养动物中 SARS-CoV-2 的感染情况。
进行了一项横断面分子监测研究，采集了与 COVID-19 患者同住的猫和狗的口腔和直肠拭子。
在与 COVID-19 患者同住的一只猫中发现了 SARS-CoV-2。基因组测序显示，B.1.111 谱系导致了猫的感染。无法对主人的样本进行测序。该谱系在哥伦比亚占主导地位，该变体的特征是存在 D614D 和 Q57H 突变。
本工作是哥伦比亚首例有全基因组测序的 SARS-CoV-2 感染猫的报告。它强调了检测可能促进这种新型冠状病毒传播能力的 SARS-CoV-2 突变的重要性。关于人传猫再传人感染的信息仍存在很大差距；我们鼓励 COVID-19 患者与伴侣动物进行自我隔离。本研究的结果初步了解了 SARS-CoV-2 在哥伦比亚动物中的感染现状。
