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表现为中高危肺栓塞的巨大游离右房血栓:再灌注治疗是更好的确定性策略吗?

Large free-floating right atrial mass presenting as intermediate-high risk pulmonary embolism: is reperfusion a better definite strategy?

机构信息

Cardiology Department, Hospital Garcia de Orta EPE, Almada, Portugal.

Cardiology Department, Hospital Garcia de Orta EPE, Almada, Portugal

出版信息

BMJ Case Rep. 2022 May 11;15(5):e249225. doi: 10.1136/bcr-2022-249225.

DOI:10.1136/bcr-2022-249225
PMID:35545309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9096487/
Abstract

We present a woman in her 60s diagnosed with an intermediate-high risk acute pulmonary embolism and a large, non-serpiginous right atrial (RA) mass. Conservative therapy with unfractionated heparin was started and further assessment of the mass with cardiac MRI suggested thrombus as the most likely diagnosis. Despite 1 month of anticoagulation, mass size remained stable and surgical RA embolectomy and left pulmonary endarterectomy was performed. Histopathology confirmed thrombus. The patient died 10 weeks after surgery.

摘要

我们报告了一位 60 多岁的女性患者,诊断为中高危急性肺栓塞和巨大、非匐行性右心房(RA)肿块。开始使用未分级肝素进行保守治疗,并对肿块进行心脏 MRI 进一步评估,提示血栓最可能是诊断。尽管抗凝治疗 1 个月,肿块大小仍保持稳定,因此进行了 RA 血栓切除术和左肺动脉内膜切除术。组织病理学证实为血栓。患者在手术后 10 周死亡。

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Large free-floating right atrial mass presenting as intermediate-high risk pulmonary embolism: is reperfusion a better definite strategy?表现为中高危肺栓塞的巨大游离右房血栓:再灌注治疗是更好的确定性策略吗?
BMJ Case Rep. 2022 May 11;15(5):e249225. doi: 10.1136/bcr-2022-249225.
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本文引用的文献

1
Warfarin versus direct oral anticoagulants for treating left ventricular thrombus: a systematic review and meta-analysis.华法林与直接口服抗凝剂治疗左心室血栓的系统评价和荟萃分析。
Thromb J. 2021 Feb 1;19(1):7. doi: 10.1186/s12959-021-00259-w.
2
Cardiac Tumors: Diagnosis, Prognosis, and Treatment.心脏肿瘤:诊断、预后和治疗。
Curr Cardiol Rep. 2020 Oct 10;22(12):169. doi: 10.1007/s11886-020-01420-z.
3
Comprehensive review of the impact of direct oral anticoagulants on thrombophilia diagnostic tests: Practical recommendations for the laboratory.直接口服抗凝剂对血栓形成倾向诊断试验影响的综合评价:实验室实用建议。
Int J Lab Hematol. 2021 Feb;43(1):7-20. doi: 10.1111/ijlh.13342. Epub 2020 Sep 18.
4
2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS).2019年欧洲心脏病学会(ESC)与欧洲呼吸学会(ERS)合作制定的急性肺栓塞诊断和管理指南。
Eur Heart J. 2020 Jan 21;41(4):543-603. doi: 10.1093/eurheartj/ehz405.
5
Wandering Thrombi in the Right Atrium: A Fatal Journey From the Heart to Lungs.右心房游走性血栓:从心脏到肺部的致命旅程
CASE (Phila). 2018 Oct 25;3(1):11-13. doi: 10.1016/j.case.2018.09.002. eCollection 2019 Feb.
6
Paradoxical embolism with thrombus stuck in a patent foramen ovale: a review of treatment strategies.卵圆孔未闭合并血栓栓塞的矛盾栓塞:治疗策略的回顾。
Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8885-8890. doi: 10.26355/eurrev_201812_16657.
7
Free-Floating Right Heart Thrombus with Acute Massive Pulmonary Embolism: A Case Report and Review of the Literature.游离性右心血栓伴急性大面积肺栓塞:一例报告并文献复习
J Cardiovasc Echogr. 2018 Apr-Jun;28(2):146-149. doi: 10.4103/jcecho.jcecho_64_17.
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Treatment of Right Heart Thrombi Associated with Acute Pulmonary Embolism.急性肺栓塞相关右心血栓的治疗
Am J Med. 2017 May;130(5):588-595. doi: 10.1016/j.amjmed.2016.11.027. Epub 2016 Dec 21.
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Right atrial free-floating thrombus in a patient with acute pulmonary embolism.一名急性肺栓塞患者的右心房游离血栓。
BMJ Case Rep. 2016 May 10;2016:bcr2016215414. doi: 10.1136/bcr-2016-215414.
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