Freeman Michael H, Perkins Elizabeth L, Tawfik Kareem O, O'Malley Matthew R, Labadie Robert F, Haynes David S, Bennett Marc L
The Otology Group, Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Laryngoscope. 2023 Jan;133(1):179-183. doi: 10.1002/lary.30161. Epub 2022 May 12.
Facial Paralysis in Skull Base Osteomyelitis - Comparison of Surgical and Nonsurgical Management.
To compare outcomes of surgical and nonsurgical management in cases of facial paresis secondary to skull base osteomyelitis.
A 14 patients presenting with skull base osteomyelitis complicated by facial nerve paresis at a single tertiary referral center from 2009 to 2019 were retrospectively reviewed. Patients were treated with medical therapy with or without surgical intervention, consisting of mastoidectomy and debridement with or without facial nerve decompression. House-Brackmann (HB) Grade was the main outcome measure.
A 14 patients (average age 68 years, range 58-82 years, 71% male) were analyzed, with 5 undergoing facial nerve decompression (36%), 5 undergoing mastoidectomy without facial nerve decompression (36%), and 4 undergoing medical management alone (28%). Of the 4 patients who underwent medical therapy alone, none experienced significant improvement in facial function. Of the 5 patients who underwent facial nerve decompression, 3 patients experienced improved facial function. Of the 5 patients who underwent mastoidectomy without decompression, 4 experienced improved facial function. There was no clear link between the severity of infection and the severity of facial paresis. When comparing HB score changes before and after treatment across groups, there was no statistically significant difference seen (p = 0.47).
Mastoidectomy and debridement with or without facial nerve decompression may improve facial nerve outcomes when compared to isolated medical management, although differences were not of statistical significance. The best facial nerve recoveries occurred in patients undergoing surgery within 14 days of the onset of paralysis.
4 - Case Series Laryngoscope, 133:179-183, 2023.
颅底骨髓炎所致面瘫——手术治疗与非手术治疗的比较
比较颅底骨髓炎继发面神经麻痹病例的手术治疗与非手术治疗效果。
回顾性分析2009年至2019年在一家三级转诊中心就诊的14例颅底骨髓炎合并面神经麻痹患者。患者接受了药物治疗,部分患者接受了手术干预,包括乳突根治术及清创术,部分患者还接受了面神经减压术。House-Brackmann(HB)分级是主要的疗效评估指标。
分析了14例患者(平均年龄68岁,范围58 - 82岁,71%为男性),其中5例接受了面神经减压术(36%),5例接受了未行面神经减压的乳突根治术(36%),4例仅接受了药物治疗(28%)。仅接受药物治疗的4例患者中,面部功能均未显著改善。接受面神经减压术的5例患者中,3例面部功能有所改善。接受未减压乳突根治术的5例患者中,4例面部功能有所改善。感染严重程度与面神经麻痹严重程度之间无明显关联。比较各组治疗前后的HB评分变化,未见统计学显著差异(p = 0.47)。
与单纯药物治疗相比,行或不行面神经减压术的乳突根治术及清创术可能改善面神经预后,尽管差异无统计学意义。面瘫发作14天内接受手术的患者面神经恢复情况最佳。
4 - 病例系列 喉镜,133:179 - 183,2023年