Graduate School, Tianjin Medical University, Tianjin, 300070, People's Republic of China.
Department of Ultrasound, The Affiliated Hospital of Inner Mongolia Medial University, Hohhot, Inner Mongolia, 010050, People's Republic of China.
J Cardiothorac Surg. 2022 May 11;17(1):114. doi: 10.1186/s13019-022-01866-y.
To retrospectively analyse the potential influencing factors of CT-guided hook wire localization failure prior to thoracoscopic resection surgery of ground glass nodules (GGNs), and determine the main risk elements for localization failure.
In all, 372 patients were included in this study, with 21 patients showing localization failure. The related parameters of patients, GGNs, and localization were analysed through univariate and multiple logistic regression analysis to determine the risk factors of localization failure.
Univariate logistic regression analysis indicated that trans-fissure (odds ratio [OR] 4.896, 95% confidence interval [CI] 1.489-13.939); trans-emphysema (OR 3.538, 95% CI 1.343-8.827); localization time (OR 0.956, 95% CI 0.898-1.019); multi-nodule localization (OR 2.597, 95% CI 1.050-6.361); and pneumothorax (OR 10.326, 95% CI 3.414-44.684) were risk factors for localization failure, and the p-values of these factors were < 0.05. However, according to the results of multivariate analysis, pneumothorax (OR 5.998, 95% CI 1.680-28.342) was an exclusive risk factor for the failure of preoperative localization of GGNs.
CT-guided hook wire localization of GGNs prior to thoracoscopic surgery is often known to fail; however, the incidence is low. Pneumothorax is an independent risk factor for failure in the localization process.
回顾性分析经 CT 引导下钩丝定位在胸腔镜下磨玻璃结节（GGN）切除术前失败的潜在影响因素，并确定定位失败的主要危险因素。
共纳入 372 例患者，其中 21 例出现定位失败。通过单因素和多因素逻辑回归分析，对患者、GGN 和定位的相关参数进行分析，以确定定位失败的危险因素。
单因素逻辑回归分析表明，经裂（比值比 [OR] 4.896，95%置信区间 [CI] 1.489-13.939）；经气肿（OR 3.538，95%CI 1.343-8.827）；定位时间（OR 0.956，95%CI 0.898-1.019）；多结节定位（OR 2.597，95%CI 1.050-6.361）；气胸（OR 10.326，95%CI 3.414-44.684）是定位失败的危险因素，这些因素的 p 值均<0.05。然而，根据多因素分析的结果，气胸（OR 5.998，95%CI 1.680-28.342）是 GGN 术前定位失败的唯一危险因素。
CT 引导下钩丝定位在胸腔镜下 GGN 切除术前常发生失败，但发生率较低。气胸是定位失败的独立危险因素。
