Int J Oral Implantol (Berl). 2022 May 13;15(2):129-146.
To evaluate the clinical, radiographic and patient-related outcomes of a novel technique for digitalisation and customisation of reinforced polytetrafluoroethylene meshes in vertical ridge augmentation surgery.
A total of 10 patients (five men and five women, mean age 54 years) with vertical defects were included in the study. Prior to surgery, digital planning of bone augmentation, manufacturing of 3D printed models and replicas of the meshes and modelling of a customised reinforced polytetrafluoroethylene mesh were carried out. All patients were treated using a 50:50 mixture of xenogeneic and autogenous bone, customised reinforced polytetrafluoroethylene mesh and collagen membrane. After 6 to 9 months, computer-guided surgery was planned, the reinforced polytetrafluoroethylene mesh was removed and implants were placed in augmented sites using a fully guided surgical template. Patient-related outcomes, intraoperative timing, surgical and healing complications, vertical bone gain, bone density, pseudoperiosteum type and number and stability of implants were recorded.
All 10 patients were treated without surgical complications. Healing was largely uneventful, with the exception of one case of abscess formation without mesh exposure (exposure rate 0%). The mean duration of digital planning was 17.0 minutes, reinforced polytetrafluoroethylene mesh customisation took 9.0 minutes, and the total intraoperative time was 91.3 minutes. The mean planned bone volume was 1.52 cc, vertical bone defect depth was 6.0 ± 1.7 mm and vertical bone gain was 5.5 ± 1.9 mm; most sites showed medium bone density and a Type 1 pseudoperiosteum. All patient-related outcomes were favourable.
The preliminary results of this pilot study demonstrated the feasibility and reliability of a fully digital workflow for the customisation of reinforced polytetrafluoroethylene mesh in vertical ridge augmentation.
评估一种新型数字化和定制增强型聚四氟乙烯网在垂直牙槽嵴增量手术中的临床、影像学和患者相关结果。
共纳入 10 名（男 5 名，女 5 名，平均年龄 54 岁）垂直缺损患者。在手术前，进行了骨增量的数字化规划、3D 打印模型和网片复制品的制造以及定制增强型聚四氟乙烯网的建模。所有患者均采用 50:50 异种骨和自体骨、定制增强型聚四氟乙烯网和胶原膜混合物进行治疗。6-9 个月后，计划进行计算机引导手术，取出增强型聚四氟乙烯网，并使用全引导手术模板将种植体放置在增强部位。记录患者相关结果、术中时间、手术和愈合并发症、垂直骨增量、骨密度、假性骨膜类型和数量以及种植体的稳定性。
所有 10 名患者均无手术并发症。愈合大多顺利，除 1 例脓肿形成而无网片暴露（暴露率 0%）外。数字化规划的平均时间为 17.0 分钟，增强型聚四氟乙烯网定制需要 9.0 分钟，总手术时间为 91.3 分钟。平均计划骨量为 1.52cc，垂直骨缺损深度为 6.0±1.7mm，垂直骨增量为 5.5±1.9mm；大多数部位的骨密度为中等，假性骨膜类型为 1 型。所有患者相关结果均良好。
本初步研究结果表明，在垂直牙槽嵴增量中定制增强型聚四氟乙烯网的全数字化工作流程具有可行性和可靠性。
