From the Department of Surgery (J.S.H.), Division of Traumatology, Emergency Surgery, and Surgical Critical Care (E.J.K., K.C., S.J., P.M.R., M.J.S.), Perelman School of Medicine at the University of Pennsylvania; and School of Arts and Sciences (D.B., K.C.), University of Pennsylvania, Philadelphia, Pennsylvania.
J Trauma Acute Care Surg. 2022 Sep 1;93(3):332-339. doi: 10.1097/TA.0000000000003606. Epub 2022 May 12.
The impact of traumatic injury likely extends beyond direct physical consequences and lasts well beyond the acute injury phase. Data collection is sparse after hospital discharge, however. In this observational study, we hypothesized that sequelae of injury would last at least 6 months and sought to prospectively determine patient-reported physical, emotional, and social outcomes during this postinjury period.
We surveyed patients admitted to our Level I trauma center (July 2019 to October 2020) regarding baseline functioning and quality of life after injury, using the Patient-Reported Outcomes Measurement Information System (PROMIS-29) instrument, a primary care posttraumatic stress disorder screen, and questions on substance use, employment, and living situation. Patients were re-surveyed at 6 months. PROMIS-29 scores are reported as t scores compared with the US population. Differences between groups were analyzed using χ 2 , signed-rank, and t tests, with paired tests used for changes over time.
Three hundred sixty-two patients completed the baseline, 130 of whom completed 6-month follow-up. Those completing the 6-month survey were similar ages (43.3 ± 17.8 vs. 44.4 ± 19.0, p = 0.57), mechanism (24.7% vs. 28.0% shot or stabbed, p = 0.61), and severities (median Injury Severity Score, 9 vs. 9; p = 0.15) as those who only completed the baseline. There were 55.0% reported being hospitalized for an injury previously. Patients reported decreases in ability to participate in social roles and activities (mean t score 51.4 vs. 55.3; p = 0.011) and increases in anxiety (53.8 vs. 50.5, p = 0.011) and depression (51.0 vs. 48.7, p = 0.025). There were 26.2% that screened positive for posttraumatic stress disorder at 6 months. Employment decreased at 6 months, with 63.9% reporting being "occasionally" employed or unemployed at 6 months versus 44.6% preinjury ( p < 0.001).
The effects of injury extend beyond pain and disability, impacting several realms of life for at least 6 months following trauma. These data support the development of screening and intervention protocols for postinjury patients.
Prognostic and Epidemiologic; Level IV.
创伤的影响可能不仅局限于直接的身体后果,而且会持续很长时间,远远超出急性损伤阶段。然而,出院后的数据收集仍然很少。在这项观察性研究中,我们假设损伤的后遗症至少会持续 6 个月,并试图前瞻性地确定受伤后患者报告的身体、情绪和社会结果。
我们使用患者报告的结局测量信息系统(PROMIS-29)工具、初级保健创伤后应激障碍筛查以及关于物质使用、就业和生活状况的问题,对我院(2019 年 7 月至 2020 年 10 月)收治的一级创伤中心患者进行了关于基线功能和受伤后生活质量的调查。PROMIS-29 评分作为 t 分数与美国人群进行比较。使用 χ 2 、符号秩和 t 检验分析组间差异,配对检验用于分析随时间的变化。
362 名患者完成了基线调查,其中 130 名完成了 6 个月的随访。完成 6 个月调查的患者年龄相似(43.3 ± 17.8 岁比 44.4 ± 19.0 岁,p = 0.57),受伤机制(24.7%比 28.0%枪击或刺伤,p = 0.61)和严重程度(中位数损伤严重程度评分,9 分比 9 分;p = 0.15)与仅完成基线调查的患者相似。55.0%的患者报告曾因受伤住院治疗。患者报告社交角色和活动参与能力下降(平均 t 分数 51.4 比 55.3;p = 0.011),焦虑增加(53.8 比 50.5,p = 0.011)和抑郁(51.0 比 48.7,p = 0.025)。6 个月时,26.2%的患者创伤后应激障碍筛查呈阳性。6 个月时就业减少,63.9%的患者报告在 6 个月时“偶尔”就业或失业,而受伤前为 44.6%(p < 0.001)。
受伤的影响不仅限于疼痛和残疾,至少在创伤后 6 个月内会影响生活的多个领域。这些数据支持为受伤后患者制定筛查和干预方案。
预后和流行病学;IV 级。