Xu Xuebing, Meng Hong, Lu Yingzhou, Li Chunxi
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technolog Beijing 100029 PR China.
College of Chemical Engineering, Beijing University of Chemical Technology Beijing 100029 PR China.
RSC Adv. 2018 Aug 30;8(53):30610-30615. doi: 10.1039/c8ra05965a. eCollection 2018 Aug 24.
Efficient production of diacetone alcohol (DAA), mesityl oxide (MO) and isophorone (IP) is important for the high value utilization of acetone. For this, a novel process is proposed for the aldol condensation of acetone by refluxing on CaC, whereby 95% of total selectivity of (DAA, MO and IP) and 85% of acetone conversion are achieved simultaneously under mild conditions (56 °C, 100 kPa). This result is superior to the previously reported ones, which may be ascribed to the extremely high catalytic capacity of CaC for the aldol condensation and instant separation of the target products from the catalyst to suppress the unwanted successive condensations. Moreover, the target products may be adjusted by operation conditions. Lower temperature and higher reflux rate favour the production of DAA and MO; MO and IP are favoured otherwise. The present process integrates several functions into one unit, the basic catalysis of calcium carbide, aldol condensation of acetone, instant distillation separation of the condensates, and the hydrolysis of CaC to CH, which makes it feasible to coproduce CH and high value derivatives of acetone simultaneously.
高效生产双丙酮醇（DAA）、异亚丙基丙酮（MO）和异佛尔酮（IP）对于丙酮的高值利用至关重要。为此，提出了一种通过在CaC上回流进行丙酮羟醛缩合的新工艺，在温和条件（56°C，100 kPa）下可同时实现95%的（DAA、MO和IP）总选择性和85%的丙酮转化率。该结果优于先前报道的结果，这可能归因于CaC对羟醛缩合的极高催化能力以及目标产物与催化剂的即时分离，从而抑制了不需要的连续缩合反应。此外，目标产物可通过操作条件进行调整。较低温度和较高回流速率有利于DAA和MO的生产；否则有利于MO和IP的生产。本工艺将多种功能集成到一个单元中，包括碳化钙的基本催化、丙酮的羟醛缩合、缩合物的即时蒸馏分离以及CaC水解生成CH，这使得同时联产CH和丙酮的高值衍生物成为可能。
