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通过协作设计开发针对甲基苯丙胺使用障碍的目标管理培训。

Development of Goal Management Training for Methamphetamine Use Disorder Through Collaborative Design.

作者信息

Anderson Alexandra C, Robinson Alex H, Potter Eden, Kerley Bronte, Flynn Daphne, Lubman Dan I, Verdejo-García Antonio

机构信息

School of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Melbourne, VIC, Australia.

Monash Addiction Research Centre, Monash University, Melbourne, VIC, Australia.

出版信息

Front Psychiatry. 2022 Apr 25;13:876018. doi: 10.3389/fpsyt.2022.876018. eCollection 2022.

Abstract

BACKGROUND

Methamphetamine use disorder (MUD) is associated with executive dysfunctions, which are linked with poorer treatment outcomes including earlier drop out and relapse. However, current treatments for MUD do not address executive functions. Goal Management Training (GMT) is an evidence-based cognitive remediation program for executive dysfunction, although required modifications to enhance its relevance and application within addiction treatment settings. This study aimed to (1) tailor GMT to the key cognitive deficits and typical treatment duration of MUD; (2) explore consumers' (people with MUD) engagement with the revised program; (3) implement a prototype of the program with consumers; and (4) present the manualized standard administration to clinical service providers.

METHODS

We followed the Medical Research Council Complex Interventions Framework and employed an evidence- and person-based intervention development process. We used a four-phased approach and collaborated with neuropsychology experts, design researchers in healthcare, consumers with MUD, and clinical service providers. Each aim was addressed in a separate study phase; including content refinement and review with neuropsychology experts (phase 1), intervention design and collaboration with consumers (phase 2), prototype development and review with consumers (phase 3), and final program modifications and review with clinical stakeholders (phase 4).

RESULTS

Findings from phase 1 indicated support for targeting four cognitive processes (attention, impulse control, goal setting, and decision-making). Key feedback included the need to help habitualize cognitive strategies and to guide consumers in applying these strategies in emotionally salient situations. Findings from phases 2 and 3 indicated consumer support for the program strategies and materials but highlighted the need to further enhance the personal relevance of specific content and journal activities. Findings from phase 4 provided clinicians support for the revised program but indicated an opportunity to minimize unintended effects. We present the intervention materials for the final revised program, Goal Management Training (GMT), in line with TIDieR guidelines.

CONCLUSIONS

GMT targets key cognitive processes and is sensitive to the clinical needs of people with MUD. Our intervention development process was important for informing the active ingredients and materials for GMT, and indicated initial consumer and provider acceptability prior to conducting a clinical trial.

摘要

背景

甲基苯丙胺使用障碍(MUD)与执行功能障碍有关,而执行功能障碍又与较差的治疗结果相关,包括更早退出治疗和复发。然而,目前针对MUD的治疗方法并未涉及执行功能。目标管理训练(GMT)是一种针对执行功能障碍的循证认知修复计划,不过需要进行修改以增强其在成瘾治疗环境中的相关性和适用性。本研究旨在:(1)根据MUD的关键认知缺陷和典型治疗时长调整GMT;(2)探究消费者(患有MUD的人)对修订后计划的参与度;(3)与消费者一起实施该计划的原型;(4)向临床服务提供者展示该计划的标准化手册管理方法。

方法

我们遵循医学研究理事会复杂干预框架,并采用基于证据和个体的干预开发过程。我们采用了四阶段方法,并与神经心理学专家、医疗保健领域的设计研究人员、患有MUD的消费者以及临床服务提供者合作。每个目标在一个单独的研究阶段中解决;包括与神经心理学专家进行内容细化和审查(第1阶段)、干预设计以及与消费者合作(第2阶段)、原型开发以及与消费者审查(第3阶段),以及最终的计划修改和与临床利益相关者审查(第4阶段)。

结果

第1阶段的研究结果表明支持针对四个认知过程(注意力、冲动控制、目标设定和决策)。关键反馈包括需要帮助使认知策略习惯化,并指导消费者在情绪突出的情况下应用这些策略。第2阶段和第3阶段的研究结果表明消费者对该计划的策略和材料表示支持,但强调需要进一步增强特定内容和日志活动的个人相关性。第4阶段的研究结果为临床医生提供了对修订后计划的支持,但表明有机会将意外影响降至最低。我们根据TIDieR指南展示了最终修订计划目标管理训练(GMT)的干预材料。

结论

GMT针对关键认知过程,并且对患有MUD的人的临床需求敏感。我们的干预开发过程对于确定GMT的有效成分和材料很重要,并在进行临床试验之前表明了最初消费者和提供者的可接受性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cbf/9082590/d145be70e3d8/fpsyt-13-876018-g0001.jpg

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