National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Department of gynaecology and obstetrics, Maternal and Child healthcare hospital of Dujiangyan, Chengdu, Sichuan, China.
BMC Pediatr. 2022 May 12;22(1):264. doi: 10.1186/s12887-022-03332-z.
The infant mortality rate (IMR) is considered a basic measure of public health for countries around the world. The specific aim of our study was to provide an updated description of infant mortality rate among different regions in rural China, and assess the trends and causes of the IMR geographical disparities.
Data were collected from China's Under-5 Child Mortality Surveillance System(U5CMSS). The annual number of deaths and causes of death were adjusted using a 3-year moving average underreporting rate based on annual national data quality control results. The average annual decline rate (AADR) and the relative risk (RR) of the IMR and cause-specific infant mortality were calculated by Poisson regression and the Cochran-Mantel-Haenszel method. Data analysis was completed by SAS software.
There was an apparent decrease in infant mortality in rural China from 2010 to 2018, at the AADR of 11.0% (95%CI 9.6-12.4), 11.2% (95%CI 10.3-12.1) and 6.6% (95%CI 6.0-7.3) in the eastern, central and western rural areas, respectively. The IMR was highest in the western rural area, followed by the central and eastern rural areas. Compared with the eastern rural area, the RR of infant mortality in the central rural area remained at 1.4-1.6 and increased from 2.4 (95%CI 2.3-2.6) in 2010-2012 to 3.1 (95% CI 2.9-3.4) in 2016-2018 in the western rural area. Pneumonia, preterm birth /LBW and birth asphyxia were the leading causes of infant deaths in the western rural area. Mortality rates of these three causes fell significantly in 2010-2018 but contributed to a higher proportion of deaths in the western rural area than in the central and western rural ares.
Our study indicated that the infant mortality rate dropped significantly from 2010 to 2018, however, geographical disparities of IMR in rural China are still persist. Therefore, there is an urgent need for public health programmes and policy interventions for infants in western rural China.
婴儿死亡率(IMR)被认为是衡量世界各国公共卫生的基本指标。本研究的具体目的是提供中国农村不同地区婴儿死亡率的最新描述,并评估 IMR 地理差异的趋势和原因。
数据来自中国的 5 岁以下儿童死亡率监测系统(U5CMS)。根据年度全国数据质量控制结果,使用 3 年移动平均漏报率对死亡人数和死因进行了调整。使用泊松回归和 Cochran-Mantel-Haenszel 方法计算了 IMR 和特定病因婴儿死亡率的平均年下降率(AADR)和相对风险(RR)。数据分析使用 SAS 软件完成。
2010 年至 2018 年,中国农村婴儿死亡率明显下降,东部、中部和西部地区的 AADR 分别为 11.0%(95%CI 9.6-12.4)、11.2%(95%CI 10.3-12.1)和 6.6%(95%CI 6.0-7.3)。西部地区农村 IMR 最高,其次是中部和东部农村地区。与东部农村地区相比,中部农村地区婴儿死亡率的 RR 保持在 1.4-1.6,而西部地区从 2010-2012 年的 2.4(95%CI 2.3-2.6)增加到 2016-2018 年的 3.1(95%CI 2.9-3.4)。肺炎、早产/低出生体重和出生窒息是西部地区婴儿死亡的主要原因。2010-2018 年,这三种原因的死亡率显著下降,但在西部地区的死亡比例高于中部和东部农村地区。
本研究表明,2010 年至 2018 年,婴儿死亡率显著下降,但中国农村 IMR 的地理差异仍然存在。因此,迫切需要为西部地区农村地区的婴儿制定公共卫生计划和政策干预措施。