Department of Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Orbit. 2022 Jun;41(3):341-345. doi: 10.1080/01676830.2021.1912114.
To report the clinical characteristics and intraoperative findings of periorbital and orbital dermoid cysts and their relationship to location and rupture.
Retrospective review of 270 cases with orbital or periorbital dermoid cysts that presented over a period of 11 years. Patients were included if diagnosis of dermoid cyst was made by histopathologic analysis. Clinical characteristics and operative outcomes were recorded and analyzed with Chi-squared analyses or univariate regression. Multivariate binary logistic regression was performed to assess predictors of location and rupture.
Dermoids frequently occurred unilaterally and were more frequently described as mobile (61.5%), followed by fixed (30.8%), and partially fixed (7.7%). Dermoid rigidity was most commonly described as firm (75.5%), followed by cystic, soft, and rubbery. The most common dermoid location was superotemporal (60.4%). On Chi-squared analysis, superotemporal lesions were less likely to have orbital extension than non-superotemporal lesions (OR 0.28, 95% CI: 0.11-0.70, = .01), less likely to undergo CT (OR 0.16, 95% CI: 0.06-0.41, < .01) or MRI (OR 0.23, 95% CI: 0.13-0.41, < .01), more likely to be described as mobile (OR 2.91, 95% CI: 1.32-6.43, = .01), and less likely to rupture intraoperatively (OR 0.28, 95% CI: 0.11-0.73, = .01). No variables were associated with rupture in multivariate analysis.
Superotemporal dermoid cysts are common in the pediatric population, less likely to have orbital extension, undergo imaging, and have intraoperative rupture when compared to other locations in the orbit.
报告眼眶和眶周皮样囊肿的临床特征和术中所见及其与位置和破裂的关系。
回顾性分析了 11 年间 270 例眼眶或眶周皮样囊肿患者的资料。如果通过组织病理学分析诊断为皮样囊肿，则将患者纳入研究。记录临床特征和手术结果，并进行卡方检验或单变量回归分析。采用多变量二项逻辑回归分析评估位置和破裂的预测因素。
皮样囊肿常单侧发生，多表现为可移动（61.5%），其次为固定（30.8%）和部分固定（7.7%）。皮样囊肿的硬度多为坚实（75.5%），其次为囊性、软和橡胶样。最常见的皮样囊肿位置是眶上颞侧（60.4%）。卡方分析显示，眶上颞侧病变的眶内延伸可能性小于非眶上颞侧病变（OR 0.28，95%CI：0.11-0.70， = 0.01），行 CT 检查的可能性较小（OR 0.16，95%CI：0.06-0.41， < 0.01）或 MRI 检查的可能性较小（OR 0.23，95%CI：0.13-0.41， < 0.01），多表现为可移动（OR 2.91，95%CI：1.32-6.43， = 0.01），术中破裂的可能性较小（OR 0.28，95%CI：0.11-0.73， = 0.01）。多变量分析中，没有变量与破裂有关。
与眼眶其他部位相比，儿童眶上颞侧皮样囊肿常见，发生眶内延伸、行影像学检查和术中破裂的可能性较小。
