University Institute of Pharmaceutical Sciences, UGC-Centre of Advanced Study, Panjab University, Chandigarh, 160 014, India.
University Institute of Pharmaceutical Sciences, UGC-Centre of Advanced Study, Panjab University, Chandigarh, 160 014, India.
J Tissue Viability. 2022 Aug;31(3):374-386. doi: 10.1016/j.jtv.2022.04.010. Epub 2022 May 5.
One of the essential organs and protective barricades, the skin, needs to be taken care of early. Skin is affected by several intrinsic and extrinsic factors, and despite their morphological and pathological differences, they have many molecular similarities. As of today, various mechanisms and theories have been recommended for aging, such as cellular anility, reduced proliferative tendency, reduction in length of telomere, mutations in DNA, theory of free radical generation, and many others. In today's society, skin health is often considered an important indicator of health, which has led to an increased demand for anti-aging products. However, numerous conventional cosmetics and phytocompounds (curcumin, Vitamin E, resveratrol) utilized in anti-aging products have inimical physical and chemical attributes, including insufficient chemical stability and inadequate skin penetration bound their effectuality after topical administration. So recently, new novel nanotechnological approaches for preventing skin aging, such as liposomes, niosomes, solid lipid nanoparticles, transferosomes, ethosomes, nanostructured lipid carriers, and carbon nanotubes, are being used. Hence, the field of cosmeceutical nanomaterials is rapidly evolving, and we can look forward to seeing a variety of innovative nanotechnology-based cosmetic products be a game-changer for this multi-million anti-aging cosmetic industry.
皮肤作为人体的重要器官和保护屏障之一,需要及早护理。皮肤受到多种内在和外在因素的影响,尽管它们在形态和病理学上存在差异,但具有许多分子相似性。截至目前,已经提出了多种衰老机制和理论,如细胞衰老、增殖倾向降低、端粒长度缩短、DNA 突变、自由基生成理论等。在当今社会,皮肤健康通常被视为健康的重要指标,这导致人们对抗衰老产品的需求增加。然而,许多传统化妆品和植物化合物(姜黄素、维生素 E、白藜芦醇)在抗衰老产品中的应用存在不利的物理和化学特性,包括化学稳定性不足和经皮渗透能力有限,限制了它们经皮给药后的效果。因此,最近,人们正在使用新的新型纳米技术方法来预防皮肤衰老,例如脂质体、非离子型脂质体、固体脂质纳米粒、传递体、醇质体、纳米结构脂质载体和碳纳米管。因此,化妆品纳米材料领域正在迅速发展,我们可以期待看到各种创新的基于纳米技术的化妆品产品成为这个数百万美元抗衰老化妆品行业的变革者。