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Advances in the study of OSA and diabetic foot.阻塞性睡眠呼吸暂停与糖尿病足的研究进展。
Diabetol Metab Syndr. 2022 May 12;14(1):70. doi: 10.1186/s13098-022-00842-9.
2
Undiagnosed severe sleep apnoea and diabetic foot ulceration - a case series based hypothesis: a hitherto under emphasized factor in failure to heal.未确诊的重度睡眠呼吸暂停与糖尿病足溃疡——基于病例系列的假说:一个迄今未得到充分重视的愈合失败因素。
Diabet Med. 2016 Feb;33(2):e1-4. doi: 10.1111/dme.12813.
3
The effect of obstructive sleep apnea on amputation site healing.阻塞性睡眠呼吸暂停对截肢部位愈合的影响。
J Vasc Nurs. 2012 Jun;30(2):61-3. doi: 10.1016/j.jvn.2011.12.003.
4
Poorly designed research does not help clarify the role of hyperbaric oxygen in the treatment of chronic diabetic foot ulcers.设计不佳的研究无助于阐明高压氧在慢性糖尿病足溃疡治疗中的作用。
Diving Hyperb Med. 2016 Sep;46(3):133-134.
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Prevalence of Obstructive Sleep Apnea in Patients With Diabetic Foot Ulcers.糖尿病足溃疡患者中阻塞性睡眠呼吸暂停的患病率。
Front Endocrinol (Lausanne). 2020 Jul 14;11:416. doi: 10.3389/fendo.2020.00416. eCollection 2020.
6
Nocturnal blood pressure and nocturnal blood pressure fluctuations: the effect of short-term CPAP therapy and their association with the severity of obstructive sleep apnea.夜间血压和夜间血压波动:短期 CPAP 治疗的效果及其与阻塞性睡眠呼吸暂停严重程度的关系。
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Elevated obstructive sleep apnoea risk score is associated with poor healing of diabetic foot ulcers: a prospective cohort study.阻塞性睡眠呼吸暂停风险评分升高与糖尿病足溃疡愈合不良相关:一项前瞻性队列研究。
Diabet Med. 2018 Nov;35(11):1494-1498. doi: 10.1111/dme.13780. Epub 2018 Aug 23.
8
Improving Diabetes Self-management by Providing Continuous Positive Airway Pressure Treatment to Patients With Obstructive Sleep Apnea and Type 2 Diabetes: Qualitative Exploratory Interview Study.通过为阻塞性睡眠呼吸暂停合并2型糖尿病患者提供持续气道正压通气治疗来改善糖尿病自我管理:定性探索性访谈研究
JMIR Form Res. 2021 Jul 20;5(7):e27062. doi: 10.2196/27062.
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Obstructive Sleep Apnea and Diabetes: A State of the Art Review.阻塞性睡眠呼吸暂停与糖尿病:最新综述
Chest. 2017 Nov;152(5):1070-1086. doi: 10.1016/j.chest.2017.05.009. Epub 2017 May 17.
10
Obstructive sleep apnea and cardiovascular events in elderly patients.老年患者阻塞性睡眠呼吸暂停与心血管事件。
Expert Rev Respir Med. 2022 Feb;16(2):197-210. doi: 10.1080/17476348.2022.2030225. Epub 2022 Jan 25.

引用本文的文献

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Novel antimicrobial strategies for diabetic foot infections: addressing challenges and resistance.糖尿病足感染的新型抗菌策略:应对挑战与耐药性
Acta Diabetol. 2025 Mar;62(3):303-321. doi: 10.1007/s00592-024-02438-3. Epub 2025 Jan 6.
2
Functional Connectivity Changes in Amygdala Subregions of Obstructive Sleep Apnea Patients After Six Months of Continuous Positive Airway Pressure Treatment.持续气道正压通气治疗六个月后阻塞性睡眠呼吸暂停患者杏仁核亚区域的功能连接变化
Nat Sci Sleep. 2024 Feb 5;16:99-109. doi: 10.2147/NSS.S442253. eCollection 2024.
3
Preclinical study of diabetic foot ulcers: From pathogenesis to vivo/vitro models and clinical therapeutic transformation.糖尿病足溃疡的临床前研究:从发病机制到体内/体外模型及临床治疗转化。
Int Wound J. 2023 Dec;20(10):4394-4409. doi: 10.1111/iwj.14311. Epub 2023 Jul 12.

本文引用的文献

1
[Relationship between obstructive sleep apnea and metabolic control and chronic complications in patients with type 2 diabetes mellitus].2型糖尿病患者阻塞性睡眠呼吸暂停与代谢控制及慢性并发症之间的关系
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Jul;35(7):662-666. doi: 10.13201/j.issn.2096-7993.2021.07.020.
2
Proliferative Pathways of Vascular Smooth Muscle Cells in Response to Intermittent Hypoxia.血管平滑肌细胞对间歇性低氧的增殖途径。
Int J Mol Sci. 2019 Jun 1;20(11):2706. doi: 10.3390/ijms20112706.
3
Reassessing the effects of continuous positive airway pressure (CPAP) on arterial stiffness and peripheral blood derived CD34+ progenitor cells in subjects with sleep apnea.重新评估持续气道正压通气(CPAP)对睡眠呼吸暂停患者动脉僵硬度和外周血源性 CD34+祖细胞的影响。
Stem Cell Res Ther. 2019 May 21;10(1):147. doi: 10.1186/s13287-019-1251-8.
4
Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity.阻塞性睡眠呼吸暂停的代谢后果,特别是与糖尿病和胰岛素敏感性有关的问题。
Diabetes Metab J. 2019 Apr;43(2):144-155. doi: 10.4093/dmj.2018.0256.
5
Sleep disturbances in diabetic peripheral neuropathy patients: a clinical and polysomnographic study.糖尿病周围神经病变患者的睡眠障碍:一项临床与多导睡眠图研究
Egypt J Neurol Psychiatr Neurosurg. 2018;54(1):23. doi: 10.1186/s41983-018-0024-0. Epub 2018 Sep 4.
6
Interactions between and Shared Molecular Mechanisms of Diabetic Peripheral Neuropathy and Obstructive Sleep Apnea in Type 2 Diabetes Patients.2 型糖尿病患者糖尿病周围神经病变与阻塞性睡眠呼吸暂停的相互作用及共享分子机制。
J Diabetes Res. 2018 Jul 19;2018:3458615. doi: 10.1155/2018/3458615. eCollection 2018.
7
A Population-Based Study of the Bidirectional Association Between Obstructive Sleep Apnea and Type 2 Diabetes in Three Prospective U.S. Cohorts.基于人群的三项美国前瞻性队列研究中阻塞性睡眠呼吸暂停与 2 型糖尿病双向关联的研究。
Diabetes Care. 2018 Oct;41(10):2111-2119. doi: 10.2337/dc18-0675. Epub 2018 Aug 2.
8
Elevated obstructive sleep apnoea risk score is associated with poor healing of diabetic foot ulcers: a prospective cohort study.阻塞性睡眠呼吸暂停风险评分升高与糖尿病足溃疡愈合不良相关:一项前瞻性队列研究。
Diabet Med. 2018 Nov;35(11):1494-1498. doi: 10.1111/dme.13780. Epub 2018 Aug 23.
9
The correlation between obstructive sleep apnea and diabetic neuropathy: A meta-analysis.阻塞性睡眠呼吸暂停与糖尿病神经病变之间的相关性:一项荟萃分析。
Prim Care Diabetes. 2018 Oct;12(5):460-466. doi: 10.1016/j.pcd.2018.03.005. Epub 2018 May 1.
10
The Relationship between Diabetes-Related Complications and Obstructive Sleep Apnea in Type 2 Diabetes.2 型糖尿病患者中糖尿病相关并发症与阻塞性睡眠呼吸暂停的关系。
J Diabetes Res. 2018 Mar 7;2018:9269170. doi: 10.1155/2018/9269170. eCollection 2018.

阻塞性睡眠呼吸暂停与糖尿病足的研究进展。

Advances in the study of OSA and diabetic foot.

作者信息

Lin Jiayu, Song Hailing, Liang Meihong, Cai Zeqiang, Chen Tan, Lin Zhenyu, Zhang Jinying

机构信息

Department of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, China.

Fujian Medical University, Fuzhou, 350100, China.

出版信息

Diabetol Metab Syndr. 2022 May 12;14(1):70. doi: 10.1186/s13098-022-00842-9.

DOI:10.1186/s13098-022-00842-9
PMID:35550628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9097179/
Abstract

Diabetic foot is one of the most serious and painful chronic complications of diabetic patients, especially elderly diabetic patients. It has a high rate of death, disability and amputation. Obstructive sleep apnea (OSA) is a treatable chronic sleep disorder. Existing evidence suggests that OSA may promote the development and delay the healing of diabetic foot, and continuous positive airway pressure therapy may promote the healing of ulcers. Therefore, in the multidisciplinary diagnosis and treatment of diabetes, cooperation with sleep medicine should be strengthened, and the basic and clinical research on diabetic foot combined with OSA should be strengthened, so as to reduce the amputation rate, improve the cure rate and reduce the incidence of cardiovascular events.

摘要

糖尿病足是糖尿病患者尤其是老年糖尿病患者最严重且痛苦的慢性并发症之一。其致死、致残及截肢率很高。阻塞性睡眠呼吸暂停(OSA)是一种可治疗的慢性睡眠障碍。现有证据表明,OSA可能会促进糖尿病足的发展并延缓其愈合,持续气道正压通气治疗可能会促进溃疡愈合。因此,在糖尿病的多学科诊疗中,应加强与睡眠医学的合作,加强糖尿病足合并OSA的基础及临床研究,以降低截肢率、提高治愈率并减少心血管事件的发生率。