肠道微生物群与坏死性小肠结肠炎：了解两者关联以寻求治愈方法。
Gut microbiome and necrotizing enterocolitis: Understanding the connection to find a cure.
作者信息
Aziz Monowar, Prince Jose M, Wang Ping
机构信息
Center for Immunology and Inflammation, The Feinstein Institutes for Medical Research, Manhasset, NY, USA; Department of Surgery, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
Center for Immunology and Inflammation, The Feinstein Institutes for Medical Research, Manhasset, NY, USA; Department of Surgery, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA; Division of Pediatric Surgery, Cohen Children's Medical Center at Hofstra/Northwell, New Hyde Park, NY, USA.
出版信息
Cell Host Microbe. 2022 May 11;30(5):612-616. doi: 10.1016/j.chom.2022.04.003.
Necrotizing enterocolitis (NEC), a cause of death among premature babies, has defied therapeutics for decades. Bacterial analyses have expanded insights into NEC pathophysiology and roles of the gut microbiome. We discuss the contribution of the gut microbiome and potential therapeutics, notably lactadherin, that may promote gut homeostasis to alleviate NEC.
坏死性小肠结肠炎（NEC）是早产婴儿死亡的一个原因，几十年来一直没有有效的治疗方法。细菌分析扩展了对NEC病理生理学和肠道微生物群作用的认识。我们讨论了肠道微生物群的作用以及可能促进肠道内环境稳定以缓解NEC的潜在治疗方法，特别是乳黏附素。
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