Gorse G J, Messner R L
Arch Dermatol. 1987 Jun;123(6):766-71.
We prospectively followed inpatients receiving treatment for pressure sores to identify the better of two local treatment regimens. Twenty-seven patients with 76 pressure sores received treatment with hydrocolloid dressings (HCDs) and 25 patients with 52 pressure sores received treatment with Dakin's solution (chloramine-T)-soaked wet-to-dry dressings. Thirty-eight (73%) patients initially had severe nutritional depletion. The mean serum albumin value of the pressure sore treatment groups was lower than that of an age-matched group without pressure sores. In the HCD group, 66 (86.8%) pressure sores improved compared with 36 (69.2%) pressure sores in the wet-to-dry dressings group. The HCD regimen was more efficacious even in a subgroup of patients who received inadequate nutritional support during treatment. Adequate nutritional intake during the study was associated with better healing in both local treatment groups.
我们对接受压疮治疗的住院患者进行前瞻性随访,以确定两种局部治疗方案中哪种更好。27例患有76处压疮的患者接受了水胶体敷料(HCD)治疗,25例患有52处压疮的患者接受了含达金氏溶液(氯胺-T)的湿-干敷料治疗。38例(73%)患者最初存在严重营养消耗。压疮治疗组的平均血清白蛋白值低于无压疮的年龄匹配组。在HCD组中,66处(86.8%)压疮有所改善,而在湿-干敷料组中为36处(69.2%)。即使在治疗期间营养支持不足的患者亚组中,HCD方案也更有效。研究期间充足的营养摄入与两个局部治疗组更好的愈合相关。