Cancer Discov. 2022 Jul 6;12(7):1604-1605. doi: 10.1158/2159-8290.CD-NB2022-0036.
The engineered IL2 cytokine bempegaldesleukin fell flat in multiple late-stage clinical studies, prompting its developers-Nektar Therapeutics and Bristol Myers Squibb-to halt its clinical development. However, a pipeline of diverse IL2-based therapies may yet succeed.
工程化的白细胞介素 2 细胞因子 bempegaldesleukin 在多项后期临床试验中均以失败告终,促使其开发者——Nektar Therapeutics 和 Bristol Myers Squibb——停止了其临床开发。然而,多样化的基于白细胞介素 2 的治疗方法可能会成功。
Cancer Discov. 2022-7-6
Cancer Biother Radiopharm. 1996-10
J Immunother Cancer. 2022-4
Front Immunol. 2025-5-29
Onco Targets Ther. 2024-8-29
Cancer Immunol Immunother. 2024-6-4
Signal Transduct Target Ther. 2024-5-22
Front Immunol. 2023