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The role of the renin-angiotensin system in normotensive and hypertensive rats with varying renin status.

作者信息

Atkinson J, Boillat N, Essadki A, Lüthi P, Maranda B, Sonnay M

出版信息

Arch Int Pharmacodyn Ther. 1987 Feb;285(2):301-15.

PMID:3555376
Abstract

We have investigated the relationship between the acute blood pressure lowering effect of captopril and renin status. Differences in renin status were induced by unilateral artery clipping combined with unilateral or bilateral nephrectomy in rats. The blood pressure lowering effect of captopril correlated very closely with plasma or aortic renin across a very wide range of renin levels.

摘要

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