Tanaka K, Freeman R D, Ramoa A S
Exp Brain Res. 1987;65(3):673-5. doi: 10.1007/BF00235991.
Most cells in the visual cortex of dark-reared kittens are unselective for stimulus orientation and we examined the notion that this might be due to insufficiently developed gamma-aminobutyric acid (GABA) receptors. We recorded from cortical neurons and examined their sensitivity to iontophoretically applied GABA. As expected, most units were non-selective for orientation, but application of GABA suppressed impulse activity of these cells just as for orientation selective neurons. This result suggests that the development or maintenance of GABA receptors is not critically dependent on visual experience.
在黑暗环境中饲养的小猫视觉皮层中的大多数细胞对刺激方向没有选择性，我们研究了这种情况可能是由于γ-氨基丁酸（GABA）受体发育不充分的观点。我们记录了皮层神经元的活动，并检测了它们对离子导入GABA的敏感性。正如预期的那样，大多数神经元对方向没有选择性，但GABA的应用抑制了这些细胞的冲动活动，这与对方向有选择性的神经元的情况相同。这一结果表明，GABA受体的发育或维持并不严重依赖于视觉经验。
