Kreye Gudrun, Wasl Manuela, Dietz Andrea, Klaffel Daniela, Groselji-Strele Andrea, Eberhard Katharina, Glechner Anna
Karl Landsteiner University of Health Sciences, Dr. Karl-Dorrek-Straße 30, 3500 Krems, Austria.
Department of Internal Medicine 2, Clinical Division of Palliative Medicine, University Hospital Krems, Mitterweg 10, 3500 Krems, Austria.
Cancers (Basel). 2022 Apr 24;14(9):2131. doi: 10.3390/cancers14092131.
Aromatherapy is regularly used in the University Hospital Krems's palliative care unit. In a retrospective analysis, we investigated whether there were improvements in nausea and vomiting in patients with advanced cancers over a time span of 24 months. Data collection used the medical records of patients who were institutionally approved to receive routine aroma applications for alleviating nausea and vomiting. The efficacy of using lemon oil pads was tested with one-dimensional chi-squared tests. Sixty-six patients received 222 applications of lemon oil on cotton pads; no data were available for 17 applications. The adequate relief of nausea and vomiting was reported for 149 (73%) applications, whereas no symptom control was seen for 56 (27%) applications. For the 56 applications without symptom control, first- and second-line rescue medications were successful in 53 and 3 cases, respectively. The use of aromatherapy with lemon oil pads against nausea and vomiting was feasible for 73% of all applications. All patients who did not benefit from aromatherapy had effective symptom control with a rescue medication. Large randomized prospective trials are necessary to evaluate the benefit of the use of lemon oil pads against nausea and vomiting in patients with advanced cancer.
克雷姆斯大学医院的姑息治疗病房经常使用芳香疗法。在一项回顾性分析中，我们调查了晚期癌症患者在24个月的时间跨度内恶心和呕吐症状是否有所改善。数据收集采用了经机构批准接受常规芳香疗法以缓解恶心和呕吐的患者的病历。使用一维卡方检验来测试柠檬油垫的疗效。66名患者在棉垫上接受了222次柠檬油涂抹；17次涂抹没有可用数据。149次（73%）涂抹报告恶心和呕吐得到充分缓解，而56次（27%）涂抹未见症状控制。对于56次未控制症状的涂抹，一线和二线救援药物分别在53例和3例中取得成功。在所有涂抹中，73%的情况下使用柠檬油垫进行芳香疗法来对抗恶心和呕吐是可行的。所有未从芳香疗法中受益的患者通过救援药物都实现了有效的症状控制。有必要进行大型随机前瞻性试验来评估使用柠檬油垫对抗晚期癌症患者恶心和呕吐的益处。
