Zavodskaia I S, Bul'on V V
Farmakol Toksikol. 1987 Jan-Feb;50(1):77-80.
The involvement of the serotoninergic system in the development of neurogenic gastric lesions induced by the three-hour electrical stimulation of the immobilized rats was shown. Serotonin (0.4 mg/kg) and d,1-5-hydroxytryptophan (50 mg/kg) failed to prevent the development of neurogenic gastric lesions. Deseril (0.5 mg/kg) and BC-105 (1 mg/kg) significantly decreased the formation of hemorrhagic erosions and prevented a decrease of serotonin and norepinephrine levels as well as creatine phosphate content in the stomach tissue.
已表明血清素能系统参与了对固定大鼠进行三小时电刺激所诱发的神经源性胃部损伤的发展过程。血清素（0.4毫克/千克）和消旋5-羟色氨酸（50毫克/千克）未能预防神经源性胃部损伤的发展。氯氮卓（0.5毫克/千克）和BC-105（1毫克/千克）显著减少了出血性糜烂的形成，并防止了胃组织中血清素、去甲肾上腺素水平以及磷酸肌酸含量的降低。
