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Counteraction by 20-hydroxyecdysone of the effect of juvenile hormone on phosphorylation of ribosomal protein S6.

作者信息

Itoh K, Ueno K, Natori S

出版信息

FEBS Lett. 1987 Mar 9;213(1):85-8. doi: 10.1016/0014-5793(87)81469-2.

DOI:10.1016/0014-5793(87)81469-2
PMID:3556581
Abstract

Phosphorylation of ribosomal protein S6, induced when the fat body of Sarcophaga peregrina (flesh-fly) larvae was incubated in vitro in the presence of 32P, was found to be suppressed by juvenile hormone. This suppressive effect of juvenile hormone was counteracted by a physiological concentration of 20-hydroxyecdysone. Since 20-hydroxyecdysone is known to induce phosphorylation of S6 in vivo, this reaction was suggested to be regulated by the balance of the effects of ecdysone and juvenile hormone.

摘要

相似文献

1
Counteraction by 20-hydroxyecdysone of the effect of juvenile hormone on phosphorylation of ribosomal protein S6.
FEBS Lett. 1987 Mar 9;213(1):85-8. doi: 10.1016/0014-5793(87)81469-2.
2
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引用本文的文献

1
Drosophila homolog of the human S6 ribosomal protein is required for tumor suppression in the hematopoietic system.人类S6核糖体蛋白的果蝇同源物是造血系统肿瘤抑制所必需的。
Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11302-6. doi: 10.1073/pnas.89.23.11302.