Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol 355017, Russia.
Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Molecules. 2022 Apr 28;27(9):2808. doi: 10.3390/molecules27092808.
A highly efficient and expeditious one-pot approach towards 2-(3-oxoindolin-2-yl)acetonitriles was designed, which involves a base-assisted aldol reaction of -nitroacetophenones, followed by hydrocyanation, triggering an unusual reductive cyclization reaction.
设计了一种高效、快速的一锅法合成 2-(3-氧代吲哚啉-2-基)乙腈的方法，该方法涉及 -硝基苯乙酮的碱辅助羟醛缩合反应，然后进行氰化氢加成，引发了一种不寻常的还原环化反应。
