Bsat F A, Seoud M A
Fertil Steril. 1987 Mar;47(3):516-8. doi: 10.1016/s0015-0282(16)59066-9.
In conclusion, CC has been associated with an increased rate of multifetal pregnancy; however, after each induction cycle, pregnancy should be ruled out before start of a new induction cycle. This would prevent misinterpretations of the gestational age at delivery, and hence of maturity, and would also help prevent any potential malformation that may be caused by a yet undetected teratogenic effect of CC.
总之,克罗米芬与多胎妊娠率增加有关;然而,在每个诱导周期后,开始新的诱导周期前应排除妊娠。这将防止对分娩时胎龄的误解,进而防止对成熟度的误解,还有助于预防可能由克罗米芬尚未检测到的致畸作用引起的任何潜在畸形。