Gastrointestinal Physiology Laboratory, Hospital de Mataró, Universitat Autònoma de Barcelona, Mataró, Catalunya, Spain.
Pharmacy Department, Hospital Universitari Germans Trias i Pujol, Badalona, Catalunya, Spain.
Syst Rev. 2022 May 14;11(1):92. doi: 10.1186/s13643-022-01969-6.
Oropharyngeal dysphagia (OD) affects 40-81% of patients after stroke. A recent systematic review on the costs of OD and its main complications showed higher acute and long-term costs for those patients who developed OD, malnutrition and pneumonia after stroke. These results suggest that appropriate management of post-stroke OD could reduce clinical complications and costs. The purpose of this systematic review is to assess the available literature for healthcare interventions that are efficient or cost-effective in the management of OD.
A systematic review on economic evaluations of health care interventions will be performed on post-stroke patients with OD following PRISMA recommendations. Four bibliographic databases will be searched and a subsequent reference check will be done. English and Spanish literature will be included without date restrictions. Studies will be included if they refer to economic evaluations or in which cost savings were reported in post-stroke patients suffering OD. Studies will be excluded if they are partial economic evaluation studies, if they refer to esophageal dysphagia, or if OD is caused by causes different from stroke. Evidence will be presented and synthetised with a narrative method and using tables. Quality evaluation will be done using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement.
The protocol for this systematic review is the first step to assess the cost-effectiveness of the healthcare interventions that have been described as potential treatments for post-stroke OD. This systematic review will summarise the current evidence on the relation between cost and benefits associated with the appropriate management of OD in post-stroke patients.
PROSPERO CRD42020136245.
口咽吞咽障碍（OD）影响 40-81%的脑卒中患者。最近一项关于 OD 及其主要并发症成本的系统评价显示，脑卒中后发生 OD、营养不良和肺炎的患者急性和长期成本更高。这些结果表明，适当管理脑卒中后 OD 可减少临床并发症和成本。本系统评价的目的是评估在管理 OD 方面具有成本效益或高效的医疗干预措施的现有文献。
按照 PRISMA 建议，对脑卒中后 OD 患者进行医疗干预的经济评价系统评价。将搜索四个文献数据库，并进行后续的参考文献检查。纳入无时间限制的英语和西班牙语文献。如果研究涉及经济评价或报告了脑卒中后 OD 患者的成本节约，则纳入研究。如果研究是部分经济评价研究、涉及食管吞咽障碍，或 OD 是由不同于脑卒中的原因引起的，则将排除研究。将采用叙述性方法和表格呈现和综合证据。使用 Consolidated Health Economic Evaluation Reporting Standards (CHEERS) 声明进行质量评估。
本系统评价方案是评估已描述为脑卒中后 OD 潜在治疗方法的医疗干预措施成本效益的第一步。本系统评价将总结目前关于适当管理脑卒中后 OD 与成本效益相关的证据。
PROSPERO CRD42020136245。
