Wytock D H, Baybick J
Gastrointest Endosc. 1987 Feb;33(1):15-7. doi: 10.1016/s0016-5107(87)71477-1.
It has been suggested that a barium enema may safely follow a colorectal biopsy superficial to the muscularis propria within 24 hours, but that the colon radiograph should be postponed 3 to 7 days following a biopsy including this layer. The authors prospectively studied 67 colorectal biopsies obtained with the Wolf 3-mm (grasping) and 5-mm (cutting) proctoscopic forceps from 49 patients to determine the depth of the biopsies. The 5-mm biopsies were not significantly deeper than the 3-mm biopsies (p greater than 0.5). In 18 patients biopsied with each instrument, the 3-mm biopsy was deeper in two cases (11%), the 5-mm biopsy was deeper in three cases (17%), and the biopsies were of equal depth in 13 cases (72%). None of the biopsies with either forceps reached the muscularis propria. The authors concluded that it may be unnecessary to wait longer than 24 hours before performing a barium enema after colorectal biopsy with these forceps.
有人提出，在固有肌层浅面进行结直肠活检后24小时内可安全地进行钡剂灌肠，但在包含该层的活检后，结肠X线照片应推迟3至7天。作者前瞻性地研究了从49例患者中用Wolf 3毫米（抓取）和5毫米（切割）直肠镜钳获取的67例结直肠活检样本，以确定活检的深度。5毫米活检样本并不比3毫米活检样本明显更深（p大于0.5）。在18例分别用两种器械进行活检的患者中，3毫米活检样本在2例中更深（11%），5毫米活检样本在3例中更深（17%），活检深度相等的有13例（72%）。使用任何一种钳子进行的活检均未到达固有肌层。作者得出结论，使用这些钳子进行结直肠活检后，在进行钡剂灌肠前可能无需等待超过24小时。
