Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Int J Lab Hematol. 2022 Dec;44(6):986-987. doi: 10.1111/ijlh.13860. Epub 2022 May 15.
The author report an interesting case of relapsed diffuse large B-cell lymphoma (DLBCL) with bone marrow (BM) and peripheral blood (PB) involvement after prior cold agglutinin disease (CAD). A minority of patients with DLBCL present with CAD, and BM or PB involvement with CAD are quite rare. Differential diagnosis of patients with CAD should include DLBCL, considering the possibility of BM or even PB involvement.
作者报告了一例有趣的复发性弥漫性大 B 细胞淋巴瘤（DLBCL）病例，该患者在先前的冷凝集素病（CAD）后出现骨髓（BM）和外周血（PB）受累。少数 DLBCL 患者表现为 CAD，而 CAD 伴 BM 或 PB 受累则较为罕见。鉴于存在 BM 甚至 PB 受累的可能，CAD 患者的鉴别诊断应包括 DLBCL。
