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患者术后早期移植肾静脉血栓形成病例报告。

Case Report of Patient With Venous Thrombosis of the Transplanted Kidney in the Early Postoperative Period.

机构信息

From the Republican Research Center of Emergency Medicine, Tashkent, Uzbekistan.

出版信息

Exp Clin Transplant. 2022 May;20(Suppl 3):126-128. doi: 10.6002/ect.PediatricSymp2022.O40.

Abstract

Renal allograft thrombosis is not a rare complication of kidney transplant and usually occurs in the early period after transplant, but it can also occur later after transplant. Several factors are associated with this infamous complication. The cause of venous anastomosis thrombosis is most often inflection or twisting of the renal vein, anastomosis stenosis, hypotension, hypercoagulation, or acute rejection of the graft. Doppler ultrasonography can allow identification of signs of thrombosis in the graft vein. With early diagnosis and timely intervention, graft function can be preserved and restored. Here, we describe a 13-year-old boy with a diagnosis of chronic kidney disease that was detected in 2017. He underwent kidney transplant, and the donor was a cousin from his mother's side of the family. HLA compatibility showed HLA-A, HLA-B, and HLADR matches, with 10% cross-matches. The patient underwent heterotopic kidney transplant in the right iliac region with the imposition of an end-toside anastomosis between the kidney artery and the external iliac artery and between the renal vein and external iliac vein. After surgery, the patient's hourly diuresis did not exceed 50 mL/hour. Graft Doppler ultrasonography showed a reversible blood flow of the graft vessels with high vascular resistance index. We suspected venous anastomosis thrombosis, and the patient was urgently taken to the operating room for revision. When the external iliac vein was opened below the anastomosis, thrombosis of the external iliac vein occurred with spread of the graft to the vein, completely covering the lumen of the vein. Thrombectomy was performed with reperfusion of the transplanted kidney with Custodial solution through the artery opening. The external iliac vein and artery opening were sutured. After blood flow started, the size, consistency, and color of the kidney returned to normal.

摘要

肾移植后血栓形成并不罕见,通常发生在移植后早期,但也可发生在移植后较晚。有几个因素与这种恶名昭彰的并发症有关。静脉吻合口血栓形成的原因最常见的是肾静脉弯曲或扭曲、吻合口狭窄、低血压、高凝状态或移植物急性排斥反应。多普勒超声检查可以发现移植物静脉血栓形成的迹象。早期诊断和及时干预可以保留和恢复移植物功能。在这里,我们描述了一名 13 岁男孩,他在 2017 年被诊断为慢性肾脏病。他接受了肾移植,供体是他母亲一方的表亲。HLA 相容性显示 HLA-A、HLA-B 和 HLADR 匹配,交叉匹配率为 10%。患者在右侧髂区进行异位肾移植,在肾动脉和髂外动脉之间以及肾静脉和髂外静脉之间进行端侧吻合。手术后,患者每小时尿量不超过 50ml/h。移植多普勒超声显示移植血管的血流可逆,血管阻力指数较高。我们怀疑静脉吻合口血栓形成,紧急将患者送往手术室进行修正。当在吻合口下方打开髂外静脉时,髂外静脉发生血栓形成,移植物蔓延至静脉,完全覆盖静脉管腔。通过动脉开口用 Custodial 溶液进行血栓切除术,使移植肾再灌注。缝合髂外静脉和动脉开口。血流开始后,肾脏的大小、质地和颜色恢复正常。

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