Bartram C R, Rüdiger H W
Klin Wochenschr. 1978 Aug 1;56(15):733-41. doi: 10.1007/BF01476762.
Multiple connections exist between chromosomal aberrations and malignant tumors. It is the aim of the present article to summarize the data known so far in view of i) cancer-prone chromosome abnormalities, ii) chromosome abnormalities related to tumors and iii) chromosome abnormalities related to carcinogens. In some instances it seemed useful to discuss the findings in man in connection with the results of in vitro experimental data.
染色体畸变与恶性肿瘤之间存在多种联系。本文旨在从以下几个方面总结目前已知的数据:i)易患癌症的染色体异常;ii)与肿瘤相关的染色体异常;iii)与致癌物相关的染色体异常。在某些情况下,结合体外实验数据的结果来讨论人类的研究发现似乎是有用的。