Li Chuankui, Ma Xiaoxiao, Yang Yifan, Li Qicai, Sang Haiwei, Wang Guowen, Tao Tao, Wang Zuyi
Department of Thoracic Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233000, China.
Evid Based Complement Alternat Med. 2022 May 6;2022:4376968. doi: 10.1155/2022/4376968. eCollection 2022.
To assess the clinical efficacy of thoracoscopic lobectomy and segmentectomy in the treatment of patients with early-stage lung cancer.
A total of 70 patients with early-stage non-small cell lung cancer who were treated in our hospital from April 2018 to May 2020 were recruited and assigned at a ratio of 1 : 1 to receive either segmentectomy (observation group) or lobectomy (control group). Outcome measures included clinical efficacy, surgery-related indicators, pulmonary function indicators (forced vital capacity (FVC) and forced expiratory volume in one second (FEV1)), postoperative complications, and recurrence and metastasis.
There was no significant difference in the clinical efficacy between the two groups ( > 0.05). Segmentectomy was associated with a longer operation time and shorter hospital stay compared to lobectomy ( < 0.05). There was no statistical significance in the amount of intraoperative blood loss and the number of lymph nodes dissected ( > 0.05). Segmentectomy resulted in significantly higher FVC and FEV1 levels in patients compared to lobectomy ( < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups ( > 0.05). The two groups of patients were followed up for 12 months after the operation, and there was no recurrence or metastasis in either group.
The two surgical methods have similar efficacy and safety profiles, but for the treatment of patients with early-stage lung cancer, thoracoscopic segmentectomy is associated with a shorter hospital stay and better protection of the lung function of patients compared to lobectomy.
评估胸腔镜肺叶切除术和肺段切除术治疗早期肺癌患者的临床疗效。
选取2018年4月至2020年5月在我院接受治疗的70例早期非小细胞肺癌患者,按1∶1比例分为两组,分别接受肺段切除术(观察组)和肺叶切除术(对照组)。观察指标包括临床疗效、手术相关指标、肺功能指标(用力肺活量(FVC)和一秒用力呼气容积(FEV1))、术后并发症以及复发和转移情况。
两组临床疗效差异无统计学意义(>0.05)。与肺叶切除术相比,肺段切除术手术时间更长,住院时间更短(<0.05)。术中出血量和清扫淋巴结数目差异无统计学意义(>0.05)。与肺叶切除术相比,肺段切除术患者的FVC和FEV1水平显著更高(<0.05)。两组术后并发症发生率差异无统计学意义(>0.05)。两组患者术后随访12个月,均未出现复发或转移。
两种手术方法的疗效和安全性相似,但对于早期肺癌患者的治疗,与肺叶切除术相比,胸腔镜肺段切除术住院时间更短,对患者肺功能的保护更好。