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单孔电视辅助胸腔镜解剖性肺段切除术与肺叶切除术治疗早期非小细胞肺癌的疗效比较:一项回顾性观察研究。

Comparison of treatment outcomes between single-port video-assisted thoracoscopic anatomic segmentectomy and lobectomy for non-small cell lung cancer of early-stage: a retrospective observational study.

作者信息

Lin Yuxing, Zheng Wei, Zhu Yong, Guo Zhaohui, Zheng Bin, Chen Chun

机构信息

Thoracic Department, Fujian Medical University Union Hospital, Fuzhou 350001, China.

出版信息

J Thorac Dis. 2016 Jun;8(6):1290-6. doi: 10.21037/jtd.2016.04.65.

Abstract

BACKGROUND

There are few reports of single-port video-assisted thoracoscopic surgery (S-VATS) anatomic segmentectomy and S-VATS lobectomy for early-stage non-small cell lung cancer (NSCLC) and no comparisons between them have yet been reported. Therefore, the aim of this study was to compare the safety and efficacy of S-VATS anatomic segmentectomy and S-VATS lobectomy for early-stage NSCLC.

METHODS

In this retrospective observational study, the outcomes of 79 consecutive patients who had undergone S-VATS anatomic segmentectomy (32 patients) or S-VATS lobectomy (47 patients) for early-stage NSCLC from April 2014 to June 2015 were examined. The operation time, intraoperative blood loss, numbers of dissected lymph nodes and mediastinal nodal stations, numbers of staples used, postoperative drainage volume and duration, duration of hospital stay, costs, postoperative complications, local recurrence, and survival were compared between these two groups.

RESULTS

The postoperative drainage volume was smaller and the postoperative drainage duration shorter in the S-VATS segmentectomy than the lobectomy group (P<0.05). There were no significant differences in operation time, intraoperative blood loss, number of staples used, number and stations of dissected mediastinal lymph nodes, duration of hospital stay, costs, or postoperative complications. At the time of writing, no deaths or local recurrences had occurred in either group.

CONCLUSIONS

S-VATS segmentectomy is as safe and effective as S-VATS lobectomy. Patients who undergo S-VATS segmentectomy seem to recover faster.

摘要

背景

关于单孔电视辅助胸腔镜手术(S-VATS)解剖性肺段切除术和S-VATS肺叶切除术治疗早期非小细胞肺癌(NSCLC)的报道较少,且尚无两者之间的比较报道。因此,本研究的目的是比较S-VATS解剖性肺段切除术和S-VATS肺叶切除术治疗早期NSCLC的安全性和有效性。

方法

在这项回顾性观察研究中,检查了2014年4月至2015年6月期间连续79例因早期NSCLC接受S-VATS解剖性肺段切除术(32例)或S-VATS肺叶切除术(47例)患者的手术结果。比较了两组患者的手术时间、术中出血量、清扫淋巴结数量和纵隔淋巴结站数、使用吻合器数量、术后引流量和引流时间、住院时间、费用、术后并发症、局部复发和生存率。

结果

S-VATS肺段切除术组的术后引流量少于肺叶切除术组,术后引流时间也短于肺叶切除术组(P<0.05)。两组在手术时间、术中出血量、使用吻合器数量、清扫纵隔淋巴结数量和站数、住院时间、费用或术后并发症方面无显著差异。在撰写本文时,两组均未发生死亡或局部复发。

结论

S-VATS肺段切除术与S-VATS肺叶切除术一样安全有效。接受S-VATS肺段切除术的患者似乎恢复得更快。

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