Ng H T, Kan Y Y, Chao K C, Yuan C C, Shyu S K
Gynecol Oncol. 1987 Mar;26(3):355-63. doi: 10.1016/0090-8258(87)90027-8.
Of the 908 patients who underwent radical hysterectomy and pelvic lymphadenectomy for invasive cervical cancer from 1973 to 1983, 139 (or 15.30%) had recurrences. The recurrent rate in the 175 patients with positive pelvic lymph nodes was 32.6%, compared with a 11.2% in the 733 patients with negative nodes (P less than 0.001). This suggests that cervical cancer patients with negative nodes acquire better prognosis after surgical treatments. Not only is recurrence much less frequent in patients with negative nodes, but also the outcome of treatments is significantly in favor of such patients: (A) 51 recurrent patients refused further treatments owing to personal reasons. None survived over 3 years; (B) The survival rate is far higher for treated patients formerly with negative nodes. Sixty of the 82 patients achieved a 5-year survival of 17.74% compared with a 2-year survival of 21.64% only in 28 patients with positive nodes. This suggests that our treatments on patients with recurrent cervical cancer are more effective when the patients have previously had negative nodes, and that refusal of treatment results in quick death.
在1973年至1983年间接受根治性子宫切除术和盆腔淋巴结清扫术治疗浸润性宫颈癌的908例患者中,139例(或15.30%)出现复发。盆腔淋巴结阳性的175例患者的复发率为32.6%,而淋巴结阴性的733例患者的复发率为11.2%(P<0.001)。这表明淋巴结阴性的宫颈癌患者手术后预后较好。淋巴结阴性的患者不仅复发频率低得多,而且治疗结果明显有利于此类患者:(A)51例复发患者因个人原因拒绝进一步治疗。无一例存活超过3年;(B)既往淋巴结阴性的接受治疗患者的生存率要高得多。82例患者中有60例实现了5年生存,生存率为17.74%,而淋巴结阳性的28例患者的2年生存率仅为21.64%。这表明我们对复发性宫颈癌患者的治疗在患者既往淋巴结阴性时更有效,而且拒绝治疗会导致快速死亡。