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胸腹主动脉瘤血管腔内修复的中期结果

Midterm Outcomes for Endovascular Repair of Thoraco-Abdominal Aortic Aneurysms.

作者信息

Ulsaker Håvard, Seternes Arne, Brekken Reidar, Manstad-Hulaas Frode

机构信息

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

Norwegian National Advisory Unit on Ultrasound and Image-Guided Therapy, St. Olavs Hospital, Trondheim, Norway.

出版信息

EJVES Vasc Forum. 2022 Apr 9;56:6-10. doi: 10.1016/j.ejvsvf.2022.03.007. eCollection 2022.

Abstract

OBJECTIVE

To investigate technical and clinical outcomes in patients with thoraco-abdominal aortic aneurysms treated with the multibranched off the shelf Zenith t-Branch stent graft or a custom made device (CMD).

METHODS

A retrospective study was conducted of patients operated on at a single tertiary vascular centre in Norway. Twenty eight t-Branch and 17 CMD patients were identified. Demographic, aneurysm, and peri-operative data were summarised and compared.

RESULTS

Thirty day mortality was 4% (2/45), with mortality rates of 7% (2/28) and 0 in t-Branch and CMD patients, respectively ( = .52). Technical success was 87% (39/45), with a non-significant difference between t-Branch and CMD procedures of 89% (25/28) and 82% (14/17), respectively ( = .63). Stent graft coverage was significantly longer in t-Branch patients ( = .020). Paraparesis or paraplegia developed in 18% (5/28) of t-Branch patients and 12% (2/17) of CMD patients ( = .69), and spinal cord ischaemia was associated with Crawford type II aneurysms ( = .010) and aortic coverage >400 mm ( = .050). The estimated survival at one and two years for t-Branch patients was 93% and 88%, and 100% and 92% for CMD patients. Freedom from re-intervention was estimated at 70% and 43% at one and two years for t-Branch patients, and 58% and 50% for CMD patients.

CONCLUSION

The study showed low 30 day mortality rates, acceptable technical success rates, high medium term survival, and no statistically significant differences in clinically relevant outcomes between t-Branch and CMD patients.

摘要

目的

探讨采用现成的多分支Zenith t型分支支架移植物或定制装置(CMD)治疗胸腹主动脉瘤患者的技术和临床结果。

方法

对挪威一家单一的三级血管中心接受手术的患者进行回顾性研究。确定了28例t型分支患者和17例CMD患者。总结并比较了人口统计学、动脉瘤和围手术期数据。

结果

30天死亡率为4%(2/45),t型分支患者和CMD患者的死亡率分别为7%(2/28)和0(P = 0.52)。技术成功率为87%(39/45),t型分支和CMD手术之间无显著差异,分别为89%(25/28)和82%(14/17)(P = 0.63)。t型分支患者的支架移植物覆盖长度明显更长(P = 0.020)。18%(5/28)的t型分支患者和12%(2/17)的CMD患者发生了轻瘫或截瘫(P = 0.69),脊髓缺血与Crawford II型动脉瘤(P = 0.010)和主动脉覆盖长度>400 mm(P = 0.050)相关。t型分支患者1年和2年的估计生存率分别为93%和88%,CMD患者为100%和92%。t型分支患者1年和2年免于再次干预的估计率分别为70%和43%,CMD患者为58%和50%。

结论

该研究显示30天死亡率低,技术成功率可接受,中期生存率高,t型分支和CMD患者在临床相关结果上无统计学显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ac0/9092505/735f1f0bc6e0/gr1.jpg

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