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海马体产生的听觉先兆——并非所有“有响声”的情况都是新皮质颞叶癫痫。

Auditory aura from the hippocampus - Not all that 'rings' is neocortical temporal lobe epilepsy.

作者信息

Kumar Sujit, Nayak Dinesh Shroff, Basrur Ravi Mohan Rao, Vishwanathan Lakshminarayanapuram Gopal, Govindappa Sharath Kumar Goddu, Pramod Manithody Narayana Bhat

机构信息

Department of Neurology, Apollo Hospitals, Seshadripuram, Bangalore, India.

Department of Neurosurgery, Apollo Hospitals, Seshadripuram, Bangalore, India.

出版信息

Epilepsy Behav Rep. 2022 Apr 27;19:100548. doi: 10.1016/j.ebr.2022.100548. eCollection 2022.

Abstract

Epileptic auras provide the initial clues to identify the probable region of ictal onset. In temporal lobe epilepsies, auras are most commonly experiential or viscerosensory, when they arise from mesial structures. Whereas sensations such as vertigo and auditory hallucinations are more likely to occur from the lateral temporal lobe structures. Auditory auras have been described from the lateral temporal neocortex, Heschl's gyri, frontal operculum and posterior insula. We herein describe a patient with temporal lobe epilepsy with an auditory aura who was localized to have the onset of seizures from the hippocampus using stereotactic EEG (SEEG). Stimulation of the hippocampal contacts also reproduced the habitual auditory aura. Anterior temporal lobectomy with amygdalohippocampectomy resulted in complete seizure freedom for 3 years. This is an initial description of auditory aura elicited from the hippocampus using SEEG.

摘要

癫痫先兆为确定发作起始的可能区域提供了最初线索。在颞叶癫痫中,当先兆源于内侧结构时,最常见的是体验性或内脏感觉性先兆。而眩晕和幻听等感觉更可能源于颞叶外侧结构。听觉先兆已被描述可源于颞叶外侧新皮质、颞横回、额盖和岛叶后部。我们在此描述了一名患有颞叶癫痫且有听觉先兆的患者,通过立体定向脑电图(SEEG)定位其癫痫发作起始于海马体。刺激海马体触点也重现了惯常的听觉先兆。颞叶前部切除术加杏仁核海马切除术使患者3年无癫痫发作。这是首次使用SEEG从海马体引出听觉先兆的描述。

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