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强直性非结肠性惊厥——癫痫持续状态——作为新型冠状病毒肺炎的首发症状

Tonic non-colonic convulsions-status epilepticus- as the presenting complaint of COVID-19.

作者信息

Al Jandale Omar, Almoshantaf Mohammad Badr, Qaddah Aya, Bakkour Agyad, Mohammed Sharif Ahmed Eman

机构信息

Department of Cardiology, Damascus University, Damascus, Syria.

Department of Neurosurgery, Ibn Al-Nafees Hospital, Damascus, Syria.

出版信息

Ann Med Surg (Lond). 2022 Jun;78:103744. doi: 10.1016/j.amsu.2022.103744. Epub 2022 May 10.

DOI:10.1016/j.amsu.2022.103744
PMID:35573473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9088155/
Abstract

INTRODUCTION

COVID19 might present as neurological symptoms including headaches, dizziness, anosmia, stroke, and loss of consciousness. Cases with severe COVID-19 are more likely to be complicated by neurological symptoms, but tonic non-colonic convulsion is still a rare presentation of COVID19 as an initial symptom.

CASE PRESENTATION

A 23-years old male presented to the ambulance with a complaint of loss of consciousness for more than 1 h and tonic convulsions without clonic movements. The investigations including computed tomography for the brain and chest and lumbar puncture were within normal range and the diagnostic workup concluded that COVID-19 is the cause of the status epilepticus.

DISCUSSION

Our case demonstrates a tonic non-clonic convulsion as a possible complication for COVID-19 infection as some respiratory viruses can cause neurological symptoms. After excluding the co-incidence of other pathological etiologies, we highly suspect that the seizures in our case are generated by COVID-19 infection.

CONCLUSION

This case represents a rare case in the literature review which can increase the awareness of tonic non-clonic seizures and other neurological manifestations as the presenting symptom of the COVID19.

摘要

引言

新型冠状病毒肺炎(COVID-19)可能表现为包括头痛、头晕、嗅觉丧失、中风和意识丧失在内的神经症状。重症COVID-19病例更易出现神经症状并发症,但强直性非阵挛性惊厥作为COVID-19的首发症状仍较为罕见。

病例介绍

一名23岁男性因意识丧失超过1小时且伴有强直性惊厥(无阵挛性运动)被送往急救车。包括脑部和胸部计算机断层扫描以及腰椎穿刺在内的检查均在正常范围内,诊断检查得出结论,COVID-19是癫痫持续状态的病因。

讨论

我们的病例显示强直性非阵挛性惊厥可能是COVID-19感染的一种并发症,因为一些呼吸道病毒可引起神经症状。在排除其他病理病因的同时发生后,我们高度怀疑我们病例中的癫痫发作是由COVID-19感染引起的。

结论

该病例在文献综述中属于罕见病例,可提高对强直性非阵挛性癫痫发作及其他神经表现作为COVID-19首发症状的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92b4/9206932/18acca008eb8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92b4/9206932/18acca008eb8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92b4/9206932/18acca008eb8/gr1.jpg

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本文引用的文献

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Seizure in patients with COVID-19.COVID-19 患者的癫痫发作。
Neurol Sci. 2020 Nov;41(11):3057-3061. doi: 10.1007/s10072-020-04731-9. Epub 2020 Sep 19.
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COVID-19 and seizures: Is there a link?新型冠状病毒肺炎与癫痫发作:二者是否存在关联?
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Neurological complications of coronavirus and COVID-19.冠状病毒及新冠病毒病的神经系统并发症
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