From the Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia.
J Am Anim Hosp Assoc. 2022 May 1;58(3):129-136. doi: 10.5326/JAAHA-MS-7186.
A 10 yr old female spayed Pomeranian presented with a history of dyspnea and coughing and was diagnosed with a cranial mediastinal mass presumed to be a thymoma. Surgical removal was elected and occurred without intraoperative complications. Histopathology revealed the lesion to be a cholesterol granuloma. The patient developed a brief period of increased respiratory difficulty 3 days postoperatively. Thoracic radiographs showed mild pleural effusion and the patient improved with supportive care. Five months postoperatively, repeat thoracic radiographs revealed no evidence of recurrence or respiratory pathology. This case report describes a cholesterol granuloma in a unique location and reviews the pathogenesis/pathophysiology of this type of mass.
一只十岁雌性去势博美犬，出现呼吸困难和咳嗽的病史，被诊断为颅纵隔肿块，推测为胸腺瘤。选择手术切除，术中无并发症。组织病理学显示病变为胆固醇肉芽肿。患者术后 3 天出现短暂的呼吸困难加重。胸部 X 光片显示轻度胸腔积液，经支持治疗后患者情况改善。术后 5 个月，重复胸部 X 光片显示无复发或呼吸道病变的证据。本病例报告描述了一个独特部位的胆固醇肉芽肿，并回顾了这种类型肿块的发病机制/病理生理学。
