Universidade Federal do Paraná, Departamento de Prevenção e Reabilitação em Fisioterapia, Rua Coronel H dos Santos, Jardim das Américas, 100 Centro Politécnico, Curitiba, Paraná, Brazil, 81530-000.
Universidade Federal do Paraná, Departamento de Educação Física, Rua Coronel H dos Santos, Jardim das Américas, 100. - Centro Politécnico, Curitiba, Paraná, Brazil, 81530-000.
Ann Phys Rehabil Med. 2023 Mar;66(2):101675. doi: 10.1016/j.rehab.2022.101675. Epub 2022 Nov 30.
Frailty increases the risk of falls, disability and death in older adults. The Cardiovascular Health Study identified a frailty phenotype (the Fried Phenotype) that was primarily based on physical domains. Instruments that incorporate additional domains (e.g., cognitive, disability or mood) may more accurately identify falls.
The study aimed i) to evaluate the association between falls and the number of phenotypes identified by the Fried Phenotype and CFVI-20 scores and ii) to compare the strength of the association between falls and each frailty instrument.
This study used the CFVI-20 and the Fried Phenotype and reported falls during the last twelve months. Logistic regression models, odds ratios (ORs), and ROC curves were used to identify associations and perform comparisons (p<0.05). The reporting of the study followed the Strobe guidelines.
This study included 1,826 individuals (mean 70.9 (SD 7.3) years old). Prevalence of pre-frailty and low vulnerability was high (72% and 69%) and comparable between frailty instruments. The number of Fried phenotypes increased the odds of having fallen in the past 12 months (OR: 1.5 to 29.5) and the CFVI-20 scores (11% increase/unit change). The CFVI-20 identified falls more accurately than the Fried Phenotype (AUC: 0.68 vs. 0.60, p < 0.001).
The number of phenotypes and the CFVI-20 scores were associated with falls; continuous scores identified falls more accurately than categorical classifications. The CFVI-20 was more strongly associated with falls in community-dwelling older adults than the Fried Phenotype.
衰弱会增加老年人跌倒、残疾和死亡的风险。心血管健康研究确定了一种衰弱表型（弗里德表型），主要基于身体领域。纳入其他领域（如认知、残疾或情绪）的工具可能更准确地识别跌倒。
本研究旨在 i）评估与跌倒相关的与弗里德表型和 CFVI-20 评分识别的表型数量的关联，以及 ii）比较与每个衰弱工具相关的跌倒关联的强度。
本研究使用 CFVI-20 和弗里德表型，并报告了过去 12 个月内的跌倒情况。使用逻辑回归模型、优势比（OR）和 ROC 曲线来识别关联并进行比较（p<0.05）。本研究的报告遵循了 Strobe 指南。
本研究纳入了 1826 名个体（平均年龄 70.9（7.3）岁）。衰弱前期和低脆弱性的患病率较高（72%和 69%），且在两种衰弱工具之间相似。弗里德表型的数量增加了过去 12 个月内跌倒的几率（OR：1.5 至 29.5）和 CFVI-20 评分（单位变化增加 11%）。CFVI-20 比弗里德表型更准确地识别出跌倒（AUC：0.68 对 0.60，p < 0.001）。
表型数量和 CFVI-20 评分与跌倒相关；连续评分比分类评分更准确地识别出跌倒。与弗里德表型相比，CFVI-20 与社区居住的老年人跌倒的关联更强。
