Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, East Azerbaijan, Iran.
School of Public Health, Tabriz University of Medical Sciences, Tabriz, Iran.
Appl Nurs Res. 2022 Jun;65:151583. doi: 10.1016/j.apnr.2022.151583. Epub 2022 Apr 6.
Heart failure (HF) is a chronic disease that negatively affects different aspects of the patients' lives, diminishing their quality of life. This research studied factors that impact the health-related quality of life (HRQoL) of patients with HF, particularly medication adherence and acceptance of illness. In this cross-sectional study, data were collected from 273 patients admitted to a tertiary hospital with the diagnosis of HF. Participants' level of illness acceptance, medication adherence, and HRQoL were assessed using validated questionnaires, and data were analyzed using the regression path analysis. There was found a moderate level of acceptance of illness (24.9 ± 6.79) and low levels of medication adherence (3.44 ± 3.15) and HRQoL (53.81 ± 17.99) among participants. Gender, education, income, history of coronary artery bypass (CABG), the New York Heart Association (NYHA) class, acceptance of illness, and medication adherence were statistically significantly associated with HRQoL. Patients with diminished HRQoL were more likely to be female, less educated, have lower income, higher NYHA class, no prior CABG, low medication adherence, and low level of acceptance of illness. The final path model demonstrated a good fit with the data (χ^2/df = 1.70, CFI = 0.92, RMSEA = 0.05, and p = 0.01). Health care providers should target and promote medication adherence and the acceptance of illness as modifiable factors to help improve the HRQoL of patients with HF.
心力衰竭（HF）是一种慢性病，会对患者生活的各个方面产生负面影响，降低其生活质量。本研究探讨了影响 HF 患者健康相关生活质量（HRQoL）的因素，特别是药物依从性和疾病接受程度。在这项横断面研究中，从一家三级医院因 HF 住院的 273 名患者中收集了数据。使用经过验证的问卷评估参与者的疾病接受程度、药物依从性和 HRQoL，使用回归路径分析对数据进行分析。结果发现，参与者的疾病接受程度处于中等水平（24.9 ± 6.79），药物依从性和 HRQoL 水平较低（3.44 ± 3.15 和 53.81 ± 17.99）。性别、教育程度、收入、冠状动脉旁路移植术（CABG）史、纽约心脏病协会（NYHA）分级、疾病接受程度和药物依从性与 HRQoL 呈统计学显著相关。HRQoL 降低的患者更有可能是女性、教育程度较低、收入较低、NYHA 分级较高、无 CABG 史、药物依从性较低、疾病接受程度较低。最终路径模型与数据拟合良好（χ^2/df = 1.70，CFI = 0.92，RMSEA = 0.05，p = 0.01）。医疗保健提供者应将药物依从性和疾病接受程度作为可改变的因素，以帮助提高 HF 患者的 HRQoL。
