Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.
College of Pharmacy, Al Ain University, Abu Dhabi, UAE.
Health Qual Life Outcomes. 2023 Jul 13;21(1):73. doi: 10.1186/s12955-023-02142-w.
Heart Failure (HF) is a chronic disease associated with life-limiting symptoms that could negatively impact patients' health-related quality of life (HRQOL). This study aimed to evaluate HRQOL and explore the factors associated with poor HRQOL among patients with HF in Jordan.
This cross-sectional study used the validated Arabic version of the Minnesota Living with Heart Failure Questionnaire to assess HRQOL in outpatients with HF visiting cardiology clinics at two public hospitals in Jordan. Variables were collected from medical records and custom-designed questionnaires, including socio-demographics, biomedical variables, and disease and medication characteristics. Ordinal regression analysis was used to explore variables associated with poor HRQOL among HF patients.
Ordinal regression analysis showed that the number of HF medications (P < 0.05) and not taking a loop diuretic (P < 0.05) significantly increased HRQOL, while the number of other chronic diseases (P < 0.05), stage III/IV of HF (P < 0.01), low monthly income (P < 0.05), and being unsatisfied with the prescribed medications (P < 0.05) significantly decreased HRQOL of HF patients.
Although the current study demonstrated low HRQOL among patients with HF in Jordan, HRQOL has a considerable opportunity for improvement in those patients. Variables identified in the present study, including low monthly income, higher New York Heart Association (NYHA) classes, a higher number of comorbidities, and/or taking a loop diuretic, should be considered in future intervention programs, aiming to improve HRQOL in patients with HF.
心力衰竭(HF)是一种与限制生命的症状相关的慢性疾病,可能对患者的健康相关生活质量(HRQOL)产生负面影响。本研究旨在评估约旦 HF 患者的 HRQOL,并探讨与 HRQOL 较差相关的因素。
本横断面研究使用经过验证的阿拉伯文版明尼苏达州心力衰竭生活质量问卷评估在约旦两家公立医院心内科诊所就诊的 HF 门诊患者的 HRQOL。从病历和定制问卷中收集变量,包括社会人口统计学、生物医学变量以及疾病和药物特征。使用有序回归分析探讨与 HF 患者 HRQOL 较差相关的变量。
有序回归分析显示,HF 药物数量(P<0.05)和未服用袢利尿剂(P<0.05)显著增加 HRQOL,而其他慢性疾病数量(P<0.05)、HF Ⅲ/Ⅳ期(P<0.01)、月收入低(P<0.05)和对处方药物不满意(P<0.05)则显著降低 HF 患者的 HRQOL。
尽管目前的研究表明约旦 HF 患者的 HRQOL 较低,但 HF 患者的 HRQOL 有很大的改善空间。本研究确定的变量,包括月收入低、纽约心脏协会(NYHA)分级较高、合并症较多和/或服用袢利尿剂,应在未来的干预计划中考虑,旨在改善 HF 患者的 HRQOL。