Faculty of Kinesiology, Sport, and Recreation, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Faculty of Kinesiology, Sport, and Recreation, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Clin Genitourin Cancer. 2022 Oct;20(5):e369-e379. doi: 10.1016/j.clgc.2022.04.003. Epub 2022 Apr 21.
Physical activity (PA) helps many cancer patients improve health-related fitness, treatment-related side effects, quality of life, and possibly survival; however, limited research has been conducted in patients with kidney cancer (KC). The aim of this scoping review focused on PA in patients with KC was to summarize current findings, delineate strengths and limitations, and provide key recommendations for future research. A scoping review was conducted and reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews guidelines. The electronic databases of PubMed and Cochrane Library were screened for studies on October 14, 2021, and the search was updated on October 31, 2021. The data were abstracted and synthesized by study design. A total of 17 articles from nine independent studies were identified including 1 cross-sectional study (n = 8 articles), 1 randomized controlled trial (n = 2 articles) and 7 cohort studies (n = 7 articles). The cross-sectional study and randomized controlled trial reported on PA participation rates, preferences, social-cognitive correlates, and quality of life in patients with KC. The 7 cohort studies mostly reported on the risk of KC mortality in general population samples. Overall, no conclusions can be drawn from current research on the safety, feasibility, and efficacy (benefits and harms) of PA in patients with KC. Future research is urgently needed on PA in patients with KC, taking into account their unique disease- and treatment-related factors. This research is necessary to inform clinical exercise guidelines in this understudied cancer patient group.
身体活动（PA）有助于许多癌症患者改善健康相关的适应性、治疗相关的副作用、生活质量，并可能提高生存率；然而，针对肾癌（KC）患者的身体活动研究有限。本次范围综述的目的聚焦于 KC 患者的身体活动，旨在总结当前研究结果，描述其优势和局限性，并为未来研究提供关键建议。按照系统评价和荟萃分析扩展范围综述的首选报告项目进行了范围综述，并按照该指南进行了报告。2021 年 10 月 14 日对 PubMed 和 Cochrane Library 电子数据库进行了研究筛选，并于 2021 年 10 月 31 日进行了更新。根据研究设计对数据进行了提取和综合。共确定了 9 项独立研究中的 17 篇文章，包括 1 项横断面研究（n=8 篇）、1 项随机对照试验（n=2 篇）和 7 项队列研究（n=7 篇）。横断面研究和随机对照试验报告了 KC 患者的身体活动参与率、偏好、社会认知相关性和生活质量。7 项队列研究主要报告了一般人群样本中 KC 死亡率的风险。总体而言，目前关于 KC 患者身体活动的安全性、可行性和疗效（益处和危害）的研究尚无结论。迫切需要对 KC 患者的身体活动进行研究，同时考虑到他们独特的疾病和治疗相关因素。这项研究对于为这一研究较少的癌症患者群体提供临床运动指南非常必要。
