David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Jules Stein Eye Institute, Division of Orbital and Ophthalmic Plastic Surgery, University of California, Los Angeles, California, USA.
Orbit. 2023 Dec;42(6):654-658. doi: 10.1080/01676830.2022.2072901. Epub 2022 May 17.
A 2-year-old boy presented with left periorbital edema, proptosis, hyperglobus and esotropia. Imaging revealed an inferotemporal orbital mass with adjacent bony erosion. Histological evaluation of an orbital biopsy revealed B-cell acute lymphoblastic leukemia/lymphoma (B-ALL/BLL). The patient was subsequently treated with chemotherapy. Although orbital involvement in acute myelogenous leukemia has been well-described, orbital manifestations of B-ALL/BLL are uncommon, with only a limited number of previous reports in the literature.
一位 2 岁男孩以左眼周水肿、眼球突出、眼球突出和内斜视就诊。影像学检查显示眼眶内下象限有一占位性病变,伴相邻骨侵蚀。眼眶活检组织学评估提示 B 细胞急性淋巴细胞白血病/淋巴瘤(B-ALL/BLL)。随后患者接受了化疗。尽管急性髓系白血病的眼眶累及已有充分描述,但 B-ALL/BLL 的眼眶表现并不常见,文献中仅有少数既往报道。