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一项为期 12 个月的基于家庭的运动方案对髋部骨折后功能的影响 - RCT 的二次分析。

Effects of a 12-month home-based exercise program on functioning after hip fracture - Secondary analyses of an RCT.

机构信息

Department of Rehabilitation, South Karelia Social and Health Care District (Eksote), Lappeenranta, Finland.

Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.

出版信息

J Am Geriatr Soc. 2022 Sep;70(9):2561-2570. doi: 10.1111/jgs.17824. Epub 2022 May 18.

Abstract

BACKGROUND

Long-term functional limitations are common after hip fractures. Exercise may alleviate these negative consequences but there is no consensus on an optimal training program. The objective was to study the effects of a 12-month home-based supervised, progressive exercise program on functioning, physical performance, and physical activity.

METHODS

Secondary analysis of a randomized controlled trial targeting patients with surgical repair of a hip fracture, aged ≥60 years, Mini-Mental State Examination (MMSE) score of ≥12. The participants were randomized into Exercise (n = 61) or Usual care (n = 60). Assessments at baseline, 3, 6, and 12 months included Lawton's Instrumental Activities of Daily Living (IADL), Short Physical Performance Battery (SPPB), handgrip strength, and self-reported frequency of sessions of leisure-time physical activity. Analyzed using mixed-effects models.

RESULTS

Participants' (n = 121) mean age was 81 years (SD 7), and 75% were women. The mean IADL score at baseline was 17.1 (SD 4.5) in the exercise group, and 17.4 (5.1) in the usual care group. The mean SPPB scores were 3.9 (1.6) and 4.2 (1.8), and handgrip strength was 17.7 (8.9) kg and 20.8 (8.0) kg, respectively. The age- and sex-adjusted mean changes in IADL over 12 months were 3.7 (95% CI 2.8-4.7) in the exercise and 2.0 (1.0-3.0) in the usual care group (between-group difference, p = 0.016); changes in SPPB 4.3 (3.6-4.9) and 2.1 (1.5-2.7) (p < 0.001); and changes in handgrip strength 1.2 kg (0.3-2.0) and 1.0 kg (-1.9 to -0.2) (p < 0.001), respectively. We found no between-group differences in changes in the frequency of leisure-time activity sessions.

CONCLUSION

A 12-month home-based supervised, progressive exercise program improved functioning and physical performance more than usual care among patients with hip fractures. However, the training did not increase leisure-time physical activity.

摘要

背景

髋部骨折后常见长期功能受限。锻炼可能减轻这些负面后果,但对于最佳训练方案尚无共识。本研究旨在探讨为期 12 个月的家庭监督、渐进式锻炼计划对功能、身体表现和身体活动的影响。

方法

对一项针对接受髋关节骨折手术修复、年龄≥60 岁、简易精神状态检查(MMSE)评分≥12 的患者的随机对照试验进行二次分析。参与者随机分为锻炼组(n=61)和常规护理组(n=60)。基线、3、6 和 12 个月的评估包括 Lawton 的工具性日常生活活动(IADL)、简易体能测试(SPPB)、握力和自我报告的休闲时间身体活动次数。采用混合效应模型进行分析。

结果

121 名参与者(n)的平均年龄为 81 岁(标准差 7),75%为女性。锻炼组基线时的 IADL 平均得分为 17.1(标准差 4.5),常规护理组为 17.4(5.1)。SPPB 平均得分为 3.9(1.6)和 4.2(1.8),握力分别为 17.7(8.9)kg 和 20.8(8.0)kg。经过 12 个月的年龄和性别调整后,锻炼组的 IADL 平均变化为 3.7(95%CI 2.8-4.7),常规护理组为 2.0(1.0-3.0)(组间差异,p=0.016);SPPB 的变化为 4.3(3.6-4.9)和 2.1(1.5-2.7)(p<0.001);握力的变化为 1.2kg(0.3-2.0)和 1.0kg(-1.9 至-0.2)(p<0.001)。我们没有发现组间在休闲时间活动次数变化上的差异。

结论

髋部骨折患者进行为期 12 个月的家庭监督、渐进式锻炼计划可改善功能和身体表现,优于常规护理。但是,训练并未增加休闲时间身体活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afbc/9790677/167dd83dca44/JGS-70-2561-g003.jpg

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