Center for Health Promotion, Samsung Medical Center, Seoul, Republic of Korea.
Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Medicine (Baltimore). 2022 May 13;101(19):e29197. doi: 10.1097/MD.0000000000029197.
Basaloid squamous cell carcinoma (SCC) is very rare subtype of SCC of the lung and it is important to distinguish basaloid to other subtypes of SCCs, since the prognosis of basaloid subtype is considered poorer than that of other non-basaloid subtypes of SCCs. Aim of this study was to assess computed tomography (CT) findings of basaloid SCC of the lung in 12 patients.From January 2016 to April 2021, 12 patients with surgically proven basaloid SCC of the lung were identified. CT findings were analyzed, and the imaging features were compared with histopathologic reports. Clinical and demographic features were also analyzed.Axial location of the tumor was central in 5 patients, while 7 was in peripheral. Of the 7 patients whose tumors were located in the peripheral, margin of the tumor were smooth (n = 2), lobulated (n = 2), or spiculated (n = 3). After contrast injection, net enhancement value ranged from 15.8 to 71.8 HU (median, 36.4 HU). Endobronchial growth were seen in 5 patients and these patients accompanied obstructive pneumonia or atelectasis. Internal profuse necrosis, cavitation, or calcifications were not seen.On CT, basaloid squamous cell presents as solitary nodule or mass with moderate enhancement. Tumor was located either peripheral or central compartment of the lung and cavitation was absent.
基底样鳞状细胞癌(SCC)是肺 SCC 非常罕见的亚型,重要的是要将其与其他 SCC 亚型区分开来,因为基底样亚型的预后被认为比其他非基底样 SCC 亚型差。本研究旨在评估 12 例肺基底样 SCC 的 CT 表现。从 2016 年 1 月至 2021 年 4 月,共确定了 12 例经手术证实的肺基底样 SCC 患者。分析了 CT 表现,并将影像学特征与组织病理学报告进行比较。还分析了临床和人口统计学特征。肿瘤的轴向位置 5 例为中央型,7 例为周围型。在位于外周的 7 例患者中,肿瘤边缘光滑(n=2)、分叶状(n=2)或有刺状(n=3)。造影后,净增强值范围为 15.8 至 71.8 HU(中位数为 36.4 HU)。5 例患者出现支气管内生长,这些患者伴有阻塞性肺炎或肺不张。未见内部广泛坏死、空洞或钙化。在 CT 上,基底样鳞状细胞表现为单发结节或肿块,增强程度中等。肿瘤位于肺的外周或中央区,无空洞。