对抑制基因突变频率下降特异性的直接证实。
A direct confirmation of the specificity of mutation frequency decline for suppressor mutations.
作者信息
Clarke C H
出版信息
Mol Gen Genet. 1978 Jul 4;162(3):345-6. doi: 10.1007/BF00268861.
PMID:355838
Abstract
In a phage T7-resistand and galactose-sensitive derivative of E. coli B/r trp- it has been possible to show that MFD for UV-induced mutations is specific for Trp+ reversions (mainly of an ochre suppressor-containing type) but is without effect on galactose-resistant or D-fucose-resistant (ara Cc) forward mutations.
摘要
在大肠杆菌B/r trp-的一种对T7噬菌体有抗性且对半乳糖敏感的衍生物中，已能够表明紫外线诱导突变的MFD对Trp+回复突变（主要是含赭石型抑制基因的类型）具有特异性，但对耐半乳糖或耐D-岩藻糖（ara Cc）的正向突变没有影响。
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