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30 年来，欧洲 384 例毛细胞白血病患者应用克拉屈滨作为一线治疗的多中心经验。

A 3-decade multicenter European experience with cladribine as upfront treatment in 384 patients with hairy cell leukemia.

机构信息

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli," Bologna, Italy.

Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Bologna, Italy.

出版信息

Blood Adv. 2022 Jul 26;6(14):4224-4227. doi: 10.1182/bloodadvances.2022007854.

DOI:10.1182/bloodadvances.2022007854
PMID:35584397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9327549/
Abstract

Cladribine is regarded as the first treatment of choice for symptomatic hairy cell leukemia. This large international study reports a complete response in 72% of cases and a continuous complete response in 20% of patients.

摘要

克拉屈滨被视为治疗有症状的毛细胞白血病的首选治疗方法。这项大型国际研究报告称，72%的病例有完全缓解，20%的患者持续完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9576/9327549/3b4314a59d32/advancesADV2022007854f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9576/9327549/3b4314a59d32/advancesADV2022007854f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9576/9327549/3b4314a59d32/advancesADV2022007854f1.jpg

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Droplet digital polymerase chain reaction for the assessment of disease burden in hairy cell leukemia.液滴数字聚合酶链反应评估毛细胞白血病的疾病负担。
Hematol Oncol. 2022 Feb;40(1):57-62. doi: 10.1002/hon.2932. Epub 2021 Oct 15.
3
The treatment of hairy cell leukemia with a focus on long lasting responses to cladribine: A 30-year experience.
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Blood Adv. 2023 Nov 14;7(21):6762-6766. doi: 10.1182/bloodadvances.2023010742.
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Measurable residual disease in hairy cell leukemia: Technical considerations and clinical significance.毛细胞白血病中的可测量残留病：技术考量与临床意义
Front Oncol. 2022 Nov 10;12:976374. doi: 10.3389/fonc.2022.976374. eCollection 2022.
用克拉屈滨治疗毛细胞白血病，重点关注持久缓解：30 年经验。
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